Bioscience & Health Programs & Projects | |
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DNA Profiling Standard Reference Materials
Last Updated Date: 03/15/2013 NIST has produced several PCR-based DNA Profiling Standard Reference Materials (SRMs) for the forensic community. The primary uses of these … more
Cytomegalovirus Standard Reference Material
Last Updated Date: 03/15/2013 Cytomegalovirus (CMV) is commonly carried by the general population (50% to 80%). After the initial infection the virus generally remains latent in … more
Measurement and Standards for Biotech Crop Detection and Quantification
Last Updated Date: 03/15/2013 The US agricultural system is a major exporter of raw materials such as grain and finished foods. A large part of the market consists of commodity … more
Development of Biomarker-based Systems for Cancer Detection and Therapy
Last Updated Date: 03/15/2013 Biomarkers play an increasingly important role in disease detection and treatment. As one of the Biomarker Reference Laboratories (BRLs) in the … more
Genome in a Bottle Consortium
Last Updated Date: 03/15/2013 NIST has organized the "Genome in a Bottle Consortium" to develop the reference materials, reference data, and reference methods needed … more
Development of Enhanced mRNA Amplification using Microfluidics
Last Updated Date: 03/15/2013 In conjunction with NCI/NIH, NIST is developing methods to improve mRNA amplification from small biological samples. Typical sample processing … more
Development of Standard Reference Materials for Vitamins B6 and B12 in Human Serum
Last Updated Date: 03/15/2013 Vitamins are essential to normal functioning of the human body because they serve as co-factors for important biological processes. Deficiencies … more
Development of a Standard Reference Material for Vitamin D in Human Serum
Last Updated Date: 03/15/2013 The prevalence of vitamin D deficiency/insufficiency within the general population is an area of concern. Vitamin D status is generally assessed … more
Development of Proteomics-Based Methods for Protein Quantification
Last Updated Date: 03/13/2013 NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to … more
Improving Measurement Quality in Clinical Proteomics
Last Updated Date: 03/13/2013 Through collaboration with academic and government institutes, NIST is critically evaluating and attempting to improve measurement quality in … more
Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum
Last Updated Date: 03/13/2013 Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac … more
Development of a Reference Measurement Procedure for C-Reactive Protein in Human Serum
Last Updated Date: 03/13/2013 C-reactive protein (CRP) levels in serum or plasma have been used as an indicator of inflammation and infection. Recent evidence also suggests … more
Development of an Amino Acid (in Solution) Standard Reference Material
Last Updated Date: 03/13/2013 Amino acids are the sequential components of proteins and many are essential to our physiological well-being. Their quantification by the … more
Chromatographic Separation of Unfolded Proteins for Protein Quantification
Last Updated Date: 03/13/2013 NIST is developing methods for the quantification of protein biomarkers by mass spectrometry (MS). Stable isotope labeling of proteins/peptides … more
Expression of Stable Isotopically Labeled Proteins for Use as Internal Standards for Mass Spectrometric Quantitation of Clinical Protein Biomarkers
Last Updated Date: 03/13/2013 Proteins are of significant interest as potential indicators (biomarkers) of health or disease. Clinical methods employed to measure these … more |
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