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Bioscience & Health Programs & Projects

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Fluorescence Microscope Benchmarking
Last Updated Date: 08/12/2014

We have made available a method to characterize a fluorescence microscope's performance by benchmarking the detection threshold, saturation and … more

State-resolved Biomolecular Spectroscopies
Last Updated Date: 07/03/2014

Sensitive and fully state resolved spectroscopic methods in the terahertz (THz) and ultraviolet (UV) regions are being developed to investigate … more

Molecular Imaging
Last Updated Date: 07/01/2014

Biophotonics is at the intersection of photonics and biology where light is used to image, detect, and manipulate biological materials. This … more

In Situ Measurement Techniques
Last Updated Date: 07/01/2014

Synthetic cell membrane constructs allow the simplification and complete control of a more complicated cellular system, as well as the … more

Recertification of Neutral Density SRMs for Regular Spectral Transmittance
Last Updated Date: 06/16/2014

The certification for all SRM neutral density filters expires after two years. We maintain a program to recertify such filters produced by us . … more

3D Tissue Scaffolds
Last Updated Date: 05/15/2014

Our goal is to develop advanced measurement tools and standards for measuring scaffold properties and their impact on biological response.  

Web Force-Field (WebFF) - A Smart Force Field Repository for Soft Materials
Last Updated Date: 04/17/2014

As part of our mission to support the Materials Genome Initiative (MGI), we are developing data repositories and tools that support Integrated … more

Computational Tool for Calculating Properties of Complex-Shaped Particles and Polymers
Last Updated Date: 04/16/2014

Many computational programs exist that are being used by industry for predicting properties of polymer composites, but their general predictive … more

Fluid Suspensions & Emulsions
Last Updated Date: 04/16/2014

Our primary interest is protein solution rheology and stability, involving bulk and interfacial properties and complemented by model solution … more

Protein Preservation
Last Updated Date: 04/16/2014

Our goal is to address critical measurement issues that exist regarding chemical and physical stability of biomacromolecules (proteins and DNA) in … more

Storage stability of Freeze-Dried Proteins
Last Updated Date: 04/15/2014

We are resolving critical measurement issues that prevent researchers from reliably predicting the chemical and physical storage stability of … more

Monoclonal Antibody MS Libraries
Last Updated Date: 10/21/2013

The National Institute of Standards and Technology is developing a mass spectral library of all identifiable components derived from the digestion … more

Microcalorimetry of biopharmaceuticals
Last Updated Date: 09/19/2013

We are using calorimetry to probe several key aspects of biopharmaceuticals related to safety and efficacy. Microcalorimetry can be used to … more

Optical/electrical particle measurement system
Last Updated Date: 09/16/2013

The sizing and counting of subvisible particles in the size range 2 µm to 100 µm is an essential component of product quality assurance in … more

Protein rheology measurements
Last Updated Date: 09/16/2013

Therapeutic protein solutions are highly concentrated during manufacturing purification processes and in finished dosage. At such concentrations, … more

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