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Bioscience & Health Programs & Projects

(showing 91 - 105 of 132)
Optical/electrical particle measurement system
Last Updated Date: 09/16/2013

The sizing and counting of subvisible particles in the size range 2 µm to 100 µm is an essential component of product quality assurance in … more

Surrogate protein particle standards
Last Updated Date: 09/10/2013

Protein-based drugs can degrade by aggregation into micrometer-sized particles.  Such particles, although only a minute fraction of the total … more

Chinese hamster ovary (CHO) cell line authentication
Last Updated Date: 09/09/2013

The misidentification of cell lines has been a problem in the scientific community for the past 50 years. Methods are now in place to genotype … more

Hyperspectral Image Projector (HIP)
Last Updated Date: 08/02/2013

Detecting climate change with remote sensing instruments, providing state-of-the-art surveillance imagery for security and defense, or getting the … more

Tandem Mass Spectral Library
Last Updated Date: 07/10/2013

The National Institute of Standards and Technology is responsible for an evaluated, tandem mass spectral library as an extension of the … more

Nanoplasmonics and Three-Dimensional Plasmonic Metamaterials
Last Updated Date: 06/28/2013

Metamaterials are tailor-made photonic composites--combinations of materials designed to achieve optical properties not seen in nature. The … more

Collagen Films Protocol
Last Updated Date: 05/08/2013

Background: Collagen type 1 is the most prevalent extracellular protein in connective tissue, and is part of the family of collagens that are … more

Digital PCR
Last Updated Date: 04/26/2013

Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR … more

DNA Biometrics
Last Updated Date: 03/15/2013

There is ongoing interest in utilizing DNA typing methods for biometric purposes. Forensic DNA typing using STR markers has been performed in the … more

SRM for Huntington CAG Repeat
Last Updated Date: 03/15/2013

Huntington disease is a neurodegenerative disease of midlife onset that produces choreic movements and cognitive decline, often accompanied by … more

DNA Profiling Standard Reference Materials
Last Updated Date: 03/15/2013

NIST has produced several PCR-based DNA Profiling Standard Reference Materials (SRMs) for the forensic community. The primary uses of these … more

Genome in a Bottle Consortium
Last Updated Date: 03/15/2013

NIST has organized the "Genome in a Bottle Consortium" to develop the reference materials, reference data, and reference methods needed to assess … more

Development of a Collagen Fibril Reference Material for Reproducible Cell Response
Last Updated Date: 01/11/2013

An important determinant of cellular response to drugs and toxins is the chemical and physical nature of the extracellular matrix (ECM) to which … more

Instrumented Bioreactors
Last Updated Date: 12/17/2012

Our goal is to develop novel bioreactors that combine mechanical stimulation with integrated sensing to enable real-time optimization of the … more

Traceability in Molecular Spectrophotometry
Last Updated Date: 11/20/2012

Standard Reference Materials (SRMs) and NIST Traceable Reference Materials (NTRMs) for UV/visible/NIR spectrophotometry are certified transfer … more

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