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Chemistry Portal - Overview

From the food we eat and the pharmaceuticals doctors prescribe to the paints and fuel additives we use, the National Institute of Standards and Technology (NIST) develops the technology, measurement methods, and standards to address the needs of the chemical industry.

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Programs and Projects

Protein drugs are the top selling pharmaceuticals worldwide, a hundred billion dollar industry, but also the fastest growing category of health … more

Comprehensive Two-Dimensional Gas Chromatography/Time of Flight Mass Spectrometry (GC x GC/TOF-MS)

Although conventional gas chromatography mass spectrometry (GC/MS) provides relatively high efficiency separations, the analysis of some complex, … more

Fundamental Chemical Metrology

The Chemical Sciences Division serves as the Nation’s reference laboratory for chemical compositional measurements and standards to enhance U.S. … more

Optimization of the Standard Addition Method (SAM) Using

The standard addition method (SAM) was first described by oceanographers in 1955 to overcome matrix effects in the determination of strontium in … more

Marine Environmental Metabolomics

NIST is developing NMR-based metabolomics for use as a tool to expand research on the impacts of environmental stressors on marine organisms. The … more

Development of Standard Reference Materials for Vitamin D Metabolites

The prevalence of vitamin D deficiency/insufficiency within the general population is an area of concern. Vitamin D status is generally assessed by … more

Standard Reference Photometer

The Standard Reference Photometer (SRP) Program began in the early 1980s as collaboration between NIST and the U.S. Environmental Protection … more

Continuous-wave terahertz spectrometer

The continuous-wave terahertz spectrometer makes use of two near-infrared lasers. The first laser is a fixed-frequency cw ring Ti:Saph laser … more

Laboratory Equipment - X-Ray Residual Stress

Location: E137 The diffractometer is part of the Residual Stress Program with the main purpose of measuring strains/stresses. Other possible … more

Laboratory Equipment - X-Ray Reflectometer

Location: E137 The NCNR x-ray diffractometer is configured to allow both ?/2? diffraction and reflectometry. Typically Cu radiation is used with … more

Laboratory Equipment - Milli-Q Water System

Location: E134 Please refer to the manufacturer's website for more information. more

Mass Spectrometry Tools Download page

This is temporary download page for Mass Spectrometry tools, while we continue to revamp the CHEMDATA web-site NIST MS Search program A demo … more

NIST Mass and Fragment Calculator Software

The NIST Mass and Fragment Calculator is a program written in Visual Basic which calculates the mass of an input peptide or protein sequence along … more

jb95 Spectral fitting program

A graphical user interface program, JB95 , based on a Windows 95 © API platform has been written in the C programming language to aid in the … more

Isotope Enrichment Calculator

The NIST Isotope Enrichment Calculator is a program written in Visual Basic which determines the percentage of 15 N enrichment of stable … more

Exercise Control System

The Systems Integration Division's (SID) Manufacturing & Modeling Simulation Group (MSG) worked with San Francisco Communications to support … more


* Download Expect source from SourceForge * Download Expect binaries from ActiveState * Expect Homepage Expect is a tool for automating … more

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