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Chemistry Programs & Projects

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Instrument Standards for Detection of Hazardous Chemical Vapors
Last Updated Date: 10/01/2012

The overarching goal of this project is to develop and disseminate measurement tools to improve the accuracy and reliability of chemical … more

Advanced IC Interconnects - Process Metrology and Models
Last Updated Date: 10/01/2012

The objective for Advanced IC Interconnects is to provide measurement standards and advanced measurement methods supporting metrology needs of the … more

Gas and Particulate Concentration Measurements and Standards
Last Updated Date: 10/01/2012

The objective is to develop and demonstrate accurate and robust measurement approaches that will establish optical absorption line intensities … more

Metrologies for Protein Structure, Function, and Modeling
Last Updated Date: 10/01/2012

NIST researchers in the Macromolecular Structure and Function Group are involved in a joint research program with scientists from the University … more

New Scalable Green Protocols for Processing Carbon Nanotubes
Last Updated Date: 10/01/2012

The overall aim of this project is to develop and validate general methods and protocols for purification, size-separation and dispersion of … more

Standards for Immuno-Histochemical Imaging: A Biomarker Protein Expression Chip
Last Updated Date: 10/01/2012

Immunohistochemistry (IHC) is used to visualize antigens in tissue sections by specific antigen-antibody interactions, an advantage over … more

Development of SRMs for Serum Proteomics
Last Updated Date: 10/01/2012

Serum proteomics, the detection and measurement of as many proteins in a serum sample as possible, could be an important element of personalized … more

Fundamental Interaction Mechanisms of Engineered Nanomaterials with DNA
Last Updated Date: 10/01/2012

We utilized isotope-dilution liquid chromatography/mass spectrometry (LC/MS) to determine the levels of the oxidatively damaged DNA bases, … more

Controlling Microfluidic Cell Culture Environments
Last Updated Date: 10/01/2012

NIST has taken advantage of recent technological advances to develop polymer microfluidic cell culture systems that provide a level of control … more

Relative Intensity Correction Standards for Fluorescence and Raman Spectroscopy
Last Updated Date: 10/01/2012

Luminescence measurements have become the methods of choice for new clinical and biochemical analyses due to their high selectivity and … more

Thermodynamics of Enzyme-catalyzed Reactions
Last Updated Date: 10/01/2012

To develop the thermodynamic data and methodology required for effective bioprocess engineering.

Nanoparticle Distribution in the Natural Environment
Last Updated Date: 10/01/2012

Given the substantial differences between nanoparticles (NPs) and typical organic and inorganic environmental contaminants, new methods and … more

Nanoparticle Accumulation and Distribution in Organisms
Last Updated Date: 10/01/2012

Given the substantial differences between nanoparticles (NPs) and typical organic and inorganic environmental contaminants, new experimental … more

Genotoxicity of Nanoparticles
Last Updated Date: 10/01/2012

As a result of their novel properties, nanoparticles are expected to be produced and incorporated into consumer products at exponentially … more

Determinations of Boron Deposit Quality by Neutron Depth Profiling
Last Updated Date: 10/01/2012

Straw detectors are a new concept in position-sensitive neutron detectors recently developed by Proportion Technology Inc. The detectors are … more

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