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Chemistry Programs & Projects

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Explosives Decomposition Chemistry
Last Updated Date: 03/18/2015

High-energy materials are commonly used as military explosives and as advanced propellants. The detailed chemical reactions responsible for … more

Regenerative Medicine
Last Updated Date: 03/17/2015

Our goal is to develop advanced measurement tools and standards for measuring scaffold properties and their impact on biological response.  

Connecting Thermodynamic and Dynamic Properties of Bulk and Confined Fluids
Last Updated Date: 03/16/2015

It is well known that the physical properties of a fluid can change profoundly, and often non-trivially, when placed in a confined environment. … more

Fundamental Chemical Metrology
Last Updated Date: 03/16/2015

The Chemical Sciences Division serves as the Nation’s reference laboratory for chemical compositional measurements and standards to enhance U.S. … more

Isotopes as Environmental Tracers in Archived Biological Specimens
Last Updated Date: 03/16/2015

There is increasing interest in the analytical and environmental communities in using mercury isotopic fingerprinting to identify source patterns … more

Monitoring Contaminants in the Arctic and Subarctic Using Banked Seabird Eggs
Last Updated Date: 03/16/2015

In 1999, the U.S. Fish and Wildlife Service Alaska Maritime National Wildlife Refuge (USFWS-AMNWR), the U.S. Geological Survey Biological … more

Optimization of the Standard Addition Method (SAM) Using
Last Updated Date: 03/10/2015

The standard addition method (SAM) was first described by oceanographers in 1955 to overcome matrix effects in the determination of strontium in … more

Biomanufacturing
Last Updated Date: 03/04/2015

Protein drugs are the top selling pharmaceuticals worldwide, a hundred billion dollar industry, but also the fastest growing category of health … more

Comprehensive Two-Dimensional Gas Chromatography/Time of Flight Mass Spectrometry (GC x GC/TOF-MS)
Last Updated Date: 03/03/2015

Although conventional gas chromatography mass spectrometry (GC/MS) provides relatively high efficiency separations, the analysis of some complex, … more

Marine Environmental Metabolomics
Last Updated Date: 03/02/2015

NIST is developing NMR-based metabolomics for use as a tool to expand research on the impacts of environmental stressors on marine organisms. The … more

Development of Standard Reference Materials for Vitamin D Metabolites
Last Updated Date: 02/27/2015

The prevalence of vitamin D deficiency/insufficiency within the general population is an area of concern. Vitamin D status is generally assessed by … more

Development of Standard Reference Materials for Vitamins B6 and B12 in Human Serum
Last Updated Date: 02/27/2015

Vitamins are essential to normal functioning of the human body because they serve as co-factors for important biological processes. Deficiencies in … more

Dietary Supplement Analysis Quality Assurance Program
Last Updated Date: 02/23/2015

The National Institute of Standards and Technology (NIST) has established a Dietary Supplement Laboratory Quality Assurance Program (DSQAP) in … more

Understanding Protein Solution Phase Behavior via Coarse-Grained Modeling
Last Updated Date: 02/10/2015

Much of our knowledge of protein folding comes from experiments on polypeptides in dilute solutions or from theoretical models of isolated … more

SRMs for Organic Contaminants in Human Serum, Milk, and Urine
Last Updated Date: 02/06/2015

NIST and the Centers for Disease Control and Prevention (CDC) are collaborating to develop seven new SRMs to meet the expanding needs for the … more

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