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Biomaterials Group


The Biomaterials Group develops methods and reference materials for characterizing interactions of materials and biological systems. This work is in support of biotechnology – related research areas and industries, both new and established. Our current focus areas cover dental materials, biopharmaceutics, and regenerative medicine. A major focus of the group is development of analytical methods for extracting quantitative and statistically significant information from systems of interest in a non-invasive or minimally-invasive way. These efforts are leveraged by research carried out collaboratively with Universities and other Federal Agencies to improve important aspects of health care diagnostics and therapeutics, and to improve performance of materials used in biotechnological industries. The group's activities are carried out in four project areas.


 A collage of results and products of the Biomaterials Group: dental composites; optical interferometric image of the tooth; cells within an electrospun fiber mesh; reference scaffolds for tissue engineering; computation model for sugar molecules for preserving proteins; and instrumental development of nonlinear optical imaging


Tissue Engineering—Our goal is to develop reliable tools and standards for measuring the properties of cells, biomaterials, scaffolds and tissue-engineered constructs. As regenerative medicine moves from a research …

Dental Materials Project—Our goal is to enable the development and manufacturing of biomaterials for oral health moving forward in 21st century by providing critical measurement methods and reference materials. Our …

Broadband CARS Microscopy—The traditional chemical labeling used in optical microscopy can alter cells and materials, thus impeding determination of their true structure, function and response. We are developing broadband …

Bioimaging—Our goal is to develop methods and materials for imaging-based characterization of molecular signatures that occur during cellular proliferation, differentiation and internalization, in order to …

Protein Preservation—Our goal is to address critical measurement issues that exist regarding chemical and physical stability of biomacromolecules (proteins and DNA) in hydrophilic, hydrogen-bonding glasses such as …


Material Measurement Laboratory (MML)

Biosystems and Biomaterials Division
Biomaterials Group
Sheng Lin-Gibson, Group Leader


301-975-6765 Telephone
301-975-4977 Facsimile

100 Bureau Drive, M/S 8543
Gaithersburg, MD 20899-8543