Nanofluidics

News and Updates

NIST Researchers Use Cellphone Compass to Measure Tiny Concentrations of Compounds Important for Human Health

April 1, 2024

Nearly every modern cellphone has a built-in compass, or magnetometer, that detects the direction of Earth’s magnetic field, providing critical information for

The FedTech Startup Studio’s Real-World Approach Advances Technology Transfer

March 22, 2023

Technology Transfer is an intensely dynamic field, and the process of moving federal scientific and technological research from the lab to the marketplace teems

No Fib: NIST Unmasks a Superfast Process for Nanoscale Machining

August 23, 2022

Cutting intricate patterns as small as several billionths of a meter deep and wide, the focused ion beam (FIB) is an essential tool for deconstructing and

Projects and Programs

viral vector illustration with RNA seen within the capsid

Gene Delivery Particle Analysis with High-Throughput Light Scattering Microscopy

Ongoing

Measurements for minimal cells

Ongoing

Technologies to manipulate biological systems have far outpaced our ability to design the function of those systems in a predictable way. This is, in part, a

Sensing, Transport, and Simulation

Ongoing

The transport of particles through a region of space acquires an imprint of local information that enables sensing, such as detecting the presence of a

Optimal Diffusion Coefficient Estimation in Single-Particle Tracking (Archived)

Completed

Single-particle tracking is a powerful tool for probing the transport behavior and local environmental properties of individual nanoparticles in liquid

Publications

Relaxation times and dynamic behavior of an optofluidic flow meter in the nanoliter per minute regime

February 29, 2024

Author(s)

Nicholas Drachman, Paul Patrone, Gregory A. Cooksey

Accuracy and temporal resolution of flow meters are often unacceptable below the microliter per minute scale, limiting their ability to evaluate the real-time

Letter to the Editor Concerning "Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles"

May 23, 2023

Author(s)

Andrew Madison, Adam L. Pintar, Craig R. Copeland, Natalia Farkas, Samuel M. Stavis

Chromium Oxide – A Novel Sacrificial Layer Material for MEMS/NEMS and Micro/Nanofluidic Device Fabrication

August 1, 2022

Author(s)

Alokik Kanwal, Robert Ilic, Christopher Ray, Kerry Siebein, James Alexander Liddle

Free standing membranes for fluidic devices typically require long etching times due to the slow, diffusion limited exchange of etchant and etch products when

Optofluidic Flow Meter for sub–nanoliter per minute flow measurements

January 31, 2022

Author(s)

Jalal Sadeghi, Paul Patrone, Anthony J. Kearsley, Gregory A. Cooksey

Performance improvements in microfluidic systems depend on accurate measurement and control of fluids on the micro- and nanoscale, and new applications are