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Topic Area: Nanobiotechnology

Displaying records 1 to 10 of 46 records.
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1. N-methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes
Topic: Nanobiotechnology
Published: 4/1/2014
Authors: Navin C. Sabharwal, Victoria Savikhin, Joshua Turek-Herman, John M. Nicoludis, Veronika A Szalai, Liliya Yatsunyk
Abstract: Guanine quadruplexes (GQ) are four-stranded DNA structures formed by guanine-rich DNA sequences. Formation of GQs inhibits cancer cell survival, but detecting GQs in vivo has proved difficult, in part because of GQ structural diversity. Development ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914285

2. Microfluidic-Enabled of Liposomes Elucidate Size-Dependent Transdermal Transport
Topic: Nanobiotechnology
Published: 3/21/2014
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Don L. DeVoe, Julia Finkel, Mariana Junqueira, Zenaide Quezado
Abstract: Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915017

3. Steering Acoustically Propelled Nanowire Motors towards Cells in a Biologically Compatible Environment using Magnetic Fields
Topic: Nanobiotechnology
Published: 12/10/2013
Authors: Suzanne Ahmed, Wei Wang, Lamar O. Mair, Robert D. Fraleigh, Sixing Li, Luz Angelica Castro, Mauricio Hoyos, Tony Jun Huang, Thomas E. Mallouk
Abstract: The recent discovery of fuel-free propulsion of nanomotors using acoustic energy has provided a new avenue for using nanomotors in biocompatible media. Crucial to the application of nanomotors in biosensing and biomedical applications is the ability ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914385

4. Microfluidic preparation of liposomes to determine particle size influence on cellular uptake mechanisms
Topic: Nanobiotechnology
Published: 10/3/2013
Authors: Wyatt N Vreeland, Abhay U Andar, Renee R Hood, Don L. DeVoe, Peter W Swaan
Abstract: Purpose: This study investigates the cellular uptake and trafficking of liposomes in Caco-2 cells, using vesicles with distinct average diameters ranging from 40 nm-276 nm. Liposomes were prepared by microfluidic hydrodynamic flow focusing, producing ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913538

5. Quantitative Analysis of Dendron-Conjugated Cisplatin-Complexed Gold Nanoparticles Using Scanning Particle Mobility Mass Spectrometry
Topic: Nanobiotechnology
Published: 5/8/2013
Authors: De-Hao D. Tsai, Tae Joon Cho, Sherrie R. Elzey, Julien C. Gigault, Vincent A Hackley
Abstract: We report a high-resolution and traceable method to quantify the drug loading on nanoparticle-based cancer therapeutics, and demonstrate this method using a model cisplatin functionalized dendron-gold nanoparticle (AuNP) conjugate. Electrospray diffe ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912782

6. Synapsable quadruplex-mediated fibers
Topic: Nanobiotechnology
Published: 5/3/2013
Authors: Veronika A Szalai, Miguel Angel Mendez
Abstract: We have fabricated and characterized a novel DNA based nanofiber created by synergistic self-assembly of guanine quadruplex (Hoogsteen base pairing) and double-stranded DNA (Watson-Crick base pairing). The assembly of our nanofibers occurs in several ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907622

7. Surface-Engineered Nanomaterials as X-ray Absorbing Adjuvant Agents for Auger-Mediated Chemo-Radiation
Topic: Nanobiotechnology
Published: 4/30/2013
Authors: Robert Francis Cook, Sang-Min Lee, De-Hao D. Tsai, Vincent A Hackley, Martin W. Brechbiel
Abstract: We demonstrate a prototype approach to formulate gold nanoparticle (AuNP)‹based X‹ray absorbing adjuvant agents through surface‹engineering of cisplatin pharmacophore (PtII) with lipoic acid‹modified polyacrylate (denoted as PtII‹AuNPs). Design of Pt ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911911

8. Theory of Polymer-Nanopore Interactions Refined Using Molecular Dynamics Simulations
Topic: Nanobiotechnology
Published: 4/30/2013
Author: Arvind Kumar Balijepalli
Abstract: Molecular dynamics (MD) simulations were used to refine and extend a theoretical model that describes the interactions of single polyethylene glycol molecules (PEGs) with an α-hemolysin nanopore. A previously developed analytical model assumed ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913514

9. Surface chemistry and size independently influence the release of model therapeutic nanoparticles from poly(ethylene glycol) hydrogels
Topic: Nanobiotechnology
Published: 4/21/2013
Authors: Stephanie L. Hume, Kavita M Jeerage
Abstract: Nanoparticles have emerged as promising therapeutic and diagnostic tools, due to their unique physicochemical properties. The specific core and surface chemistries, as well as nanoparticle size,all play critical roles in particle transport and inte ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912443

10. Temperature sculpting in yoctoliter volumes
Topic: Nanobiotechnology
Published: 2/14/2013
Authors: Joseph E Reiner, Joseph William Robertson, Daniel L Burden, Lisa K Burden, Arvind Kumar Balijepalli, John J Kasianowicz
Abstract: The ability to perturb large ensembles of molecules from equilibrium led to major advances in understanding reaction mechanisms in chemistry and biology. Here, we demonstrate the ability to control, measure, and make use of rapid temperature changes ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=910990



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