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You searched on: Topic Area: Nanobiotechnology

Displaying records 1 to 10 of 31 records.
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1. A method to determine the number of nanoparticles in a cluster using conventional optical microscopes
Topic: Nanobiotechnology
Published: 9/10/2015
Authors: Hyeong Gon (Hyeonggon) Kang, Ravikiran Attota, Premsagar Purushotham Kavuri, Vipin Nagnath Tondare, Andras Vladar

2. Microfluidic Remote Loading for Rapid Single-Step Liposomal Drug Preparation
Topic: Nanobiotechnology
Published: 7/29/2014
Authors: Wyatt N Vreeland, Renee R Hood, Don L. DeVoe
Abstract: Here we report a microfluidic system that enables rapid and efficient remote loading of amphipathic drugs into nanoscale liposomes, combining liposome synthesis and remote drug loading in a continuous integrated process. Unlike established bulk m ...

3. Resolving three-dimensional shape of sub-50 nm wide lines with nanometer-scale sensitivity using conventional optical microscopes
Topic: Nanobiotechnology
Published: 7/29/2014
Authors: Ravikiran Attota, Ronald G Dixson
Abstract: We experimentally demonstrate that the three-dimensional (3-D) shape variations of nanometer-scale objects can be resolved and measured with sub-nanometer scale sensitivity using conventional optical microscopes by analyzing 3-D optical data using th ...

4. A Facile Route to the Synthesis of Monodisperse Nanoscale Liposomes Using 3D Microfluidic Hydrodynamic Focusing in a Concentric Capillary Array
Topic: Nanobiotechnology
Published: 5/14/2014
Authors: Wyatt N Vreeland, Renee R Hood, Don L. DeVoe, Francisco Javier Atencia, Donna M. Omiatek
Abstract: A novel microscale device has been developed to enable the one-step continuous flow assembly of monodisperse nanoscale liposomes using three-dimensional microfluidic hydrodynamic focusing (3D-MHF) in a radially symmetric capillary array. The 3D-M ...

5. N-methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes
Topic: Nanobiotechnology
Published: 4/1/2014
Authors: Navin C. Sabharwal, Victoria Savikhin, Joshua Turek-Herman, John M. Nicoludis, Veronika A Szalai, Liliya Yatsunyk
Abstract: Guanine quadruplexes (GQ) are four-stranded DNA structures formed by guanine-rich DNA sequences. Formation of GQs inhibits cancer cell survival, but detecting GQs in vivo has proved difficult, in part because of GQ structural diversity. Development ...

6. Microfluidic-Enabled of Liposomes Elucidate Size-Dependent Transdermal Transport
Topic: Nanobiotechnology
Published: 3/21/2014
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Don L. DeVoe, Julia Finkel, Mariana Junqueira, Zenaide Quezado
Abstract: Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee ...

7. Controlled Formation and Characterization of Dithiothreitol-Conjugated Gold Nanoparticle Clusters
Topic: Nanobiotechnology
Published: 3/5/2014
Authors: De-Hao D. Tsai, Tae Joon Cho, Frank W DelRio, Justin M Gorham, Jiwen Zheng, Jiaojie Tan, Michael Russel Zachariah, Vincent A Hackley
Abstract: We report a systematic study of the controlled formation of discrete-size gold nanoparticle clusters (GNCs) by interaction with the reducing agent dithiothreitol (DTT). Asymmetric-flow field flow fractionation and electrospray differential mobility a ...

8. Steering Acoustically Propelled Nanowire Motors towards Cells in a Biologically Compatible Environment using Magnetic Fields
Topic: Nanobiotechnology
Published: 12/10/2013
Authors: Suzanne Ahmed, Wei Wang, Lamar O. Mair, Robert D. Fraleigh, Sixing Li, Luz Angelica Castro, Mauricio Hoyos, Tony Jun Huang, Thomas E. Mallouk
Abstract: The recent discovery of fuel-free propulsion of nanomotors using acoustic energy has provided a new avenue for using nanomotors in biocompatible media. Crucial to the application of nanomotors in biosensing and biomedical applications is the ability ...

9. Quantitative Analysis of Dendron-Conjugated Cisplatin-Complexed Gold Nanoparticles Using Scanning Particle Mobility Mass Spectrometry
Topic: Nanobiotechnology
Published: 5/8/2013
Authors: De-Hao D. Tsai, Tae Joon Cho, Sherrie R. Elzey, Julien C. Gigault, Vincent A Hackley
Abstract: We report a high-resolution and traceable method to quantify the drug loading on nanoparticle-based cancer therapeutics, and demonstrate this method using a model cisplatin functionalized dendron-gold nanoparticle (AuNP) conjugate. Electrospray diffe ...

10. Synapsable quadruplex-mediated fibers
Topic: Nanobiotechnology
Published: 5/3/2013
Authors: Veronika A Szalai, Miguel Angel Mendez
Abstract: We have fabricated and characterized a novel DNA based nanofiber created by synergistic self-assembly of guanine quadruplex (Hoogsteen base pairing) and double-stranded DNA (Watson-Crick base pairing). The assembly of our nanofibers occurs in several ...

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