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You searched on: Topic Area: Diagnostics

Displaying records 1 to 10 of 24 records.
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1. Candidate Reference Measurement Procedure for the Determination of 24R,25-Dihydroxyvitamin D3 in Human Serum using Isotope-Dilution Liquid Chromatography-Tandem Mass Spectrometry
Topic: Diagnostics
Published: 7/14/2015
Authors: Susan Shu Cheng Tai, Michael A Nelson
Abstract: The two major forms of vitamin D, vitamin D3 and vitamin D2, are metabolized in the liver through hydroxylation to 25-hydroxyvitamin D species, and then further hydroxylated in the kidney to various dihydroxyvitamin D species. 24R,25-Dihydroxyvitami ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=918563

2. Genomic Reference Materials for Clinical Application
Topic: Diagnostics
Published: 11/21/2014
Authors: Justin M Zook, Marc L Salit
Abstract: Reference Materials are well-characterized, homogeneous, and stable samples that can be used to understand measurement performance. The Genome in a Bottle Consortium is developing whole human genome DNA Reference Materials from large batches of DNA ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913928

3. Performance Benchmarking and Intensity Calibration of a Widefield Fluorescence Microscope Using Fluorescent Glass
Topic: Diagnostics
Published: 8/11/2014
Authors: Michael W Halter, Elianna Bier, Paul C DeRose, Gregory A Cooksey, Steven J Choquette, Anne L Plant, John T Elliott
Abstract: Widefield fluorescence microscopy is a highly used tool for visually assessing biological samples and for quantifying cell responses. Despite its widespread use in high content analysis and other screening applications, few published methods exist f ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915188

4. Determining carbapenemase activity with 18O labeling and targeted mass spectrometry
Topic: Diagnostics
Published: 10/16/2013
Authors: Meiyao Wang, Yang Shen, Illarion V Turko, Daniel Nelson, Shuwei Li
Abstract: Carbapenems are broad spectrum antibiotics considered as last resort drugs to treat bacterial infections. Carbapenem-hydrolyzing β-lactamases (also called carbapenemases), however, can confer bacterial resistance and represent a serious health t ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914525

5. Quantitative Analysis of Dendron-Conjugated Cisplatin-Complexed Gold Nanoparticles Using Scanning Particle Mobility Mass Spectrometry
Topic: Diagnostics
Published: 5/8/2013
Authors: De-Hao D. Tsai, Tae Joon Cho, Sherrie R. Elzey, Julien C. Gigault, Vincent A Hackley
Abstract: We report a high-resolution and traceable method to quantify the drug loading on nanoparticle-based cancer therapeutics, and demonstrate this method using a model cisplatin functionalized dendron-gold nanoparticle (AuNP) conjugate. Electrospray diffe ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912782

6. Breast Cancer Biomarker Measurements and Standards
Topic: Diagnostics
Published: 1/24/2013
Authors: Kenneth D Cole, Lili Wang, Hua-Jun He
Abstract: Cancer is a heterogeneous disease characterized by changes in the levels and activities of important cellular proteins, including oncogenes and tumor suppressors. Genetic mutations cause changes in protein activity and protein expression levels that ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912867

7. GENERATING CELL CO-CULTURES BY RAPID CELL ADHESION ON OPPOSITE SIDES OF POLYESTER MEMBRANES
Topic: Diagnostics
Published: 10/28/2012
Authors: Conni Hanke, Petra S. Dittrich, Darwin R Reyes-Hernandez
Abstract: A cell co-culture was generated on opposite sides of a permeable polyester membrane (PET) membrane by combining dielectrophoretic (DEP) and electrostatic forces to hold cells against gravity in a multilayer microfluidic device (Figure 1). HepG2 cell ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911771

8. Simple device for rare cell capture from whole blood
Topic: Diagnostics
Published: 9/26/2012
Authors: Jason G Kralj, Samuel P Forry, Matthew S Munson, Thomas P Forbes, Chandamany Arya, Lynn Sorbara, Alessandro Tona, Sudhir Srivastava
Abstract: We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics that can provide biologists with the capabilities of the monolithic devices. We characterized the capture of MCF-7 cell ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911536

9. Developing digital tissue phantoms for hyperspectral imaging of ischemic wounds
Topic: Diagnostics
Published: 5/18/2012
Authors: David W Allen, Jeeseong Hwang, Maritoni Abatayo Litorja, Joseph Paul Rice
Abstract: Biomedical optical imaging has the potential to achieve high spatial resolution and high functional sensitivity for non-invasive assessment of ischemic wounds. However, clinical acceptance of many optical imaging devices is hampered by poor repro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=910922

10. Determination of Moisture Content of Single-Wall Carbon Nanotubes
Topic: Diagnostics
Published: 10/17/2011
Authors: Rolf Louis Zeisler, Rabia Oflaz, Ralph E. Sturgeon, Rick L Paul, Brian E Lang, Jeffrey A Fagan, Joseph W Lam, Anthony Windust, P Grinberg, Benoit Simard, Christopher T. Kingston
Abstract: Several techniques were evaluated for the establishment of reliable water/moisture content of single-wall carbon nanotubes. Karl Fischer titration (KF) provides for a direct measure of the water content and was used for benchmarking against results ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908873



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