NIST logo

Publications Portal

You searched on: Topic Area: Drugs/Pharmaceuticals

Displaying records 1 to 10 of 55 records.
Resort by: Date / Title


1. Critical Examination of the Colloidal Particle Model of Globular Proteins
Topic: Drugs/Pharmaceuticals
Published: 2/3/2015
Authors: Prasad Srinivasan Sarangapani, Steven D Hudson, Ronald Leland Jones, Jack F Douglas, Jai Avinash Pathak
Abstract: Recent studies of globular protein solutions have uniformly adopted a colloidal view of proteins as particles, a perspective that neglects the polymeric primary structure of these biological macromolecules, their intrinsic flexibility and their abi ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915903

2. The Use of Index-Matched Beads in Optical Particle Counters
Series: Journal of Research (NIST JRES)
Report Number: 119.029
Topic: Drugs/Pharmaceuticals
Published: 1/8/2015
Author: Dean C Ripple
Abstract: Although multiple methods are available for counting and sizing of protein particles over a broad range of sizes, differences in physical properties between common polystyrene-bead reference materials and the actual protein particles of interest ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916272

3. Membrane protein resistance of oligo(ethylene oxide) self-assembled monolayers
Topic: Drugs/Pharmaceuticals
Published: 7/31/2014
Authors: David J Vanderah, Marlon L Walker, David Travis Gallagher, Ryan Vierling, Fay Crawshaw
Abstract: Spectroscopic ellipsometry was used to evaluate the resistance to protein adsorption (RPA) of self- assembled monolayers (SAMs) of HS(CH2)3O(CH2CH2O)6M and [HS(CH2)3CH]2O-(CH2CH2O)6M, where M = CH3 or H, on Au. The SAMs were exposed to fibrinogen ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913472

4. Microfluidic Remote Loading for Rapid Single-Step Liposomal Drug Preparation
Topic: Drugs/Pharmaceuticals
Published: 7/29/2014
Authors: Wyatt N Vreeland, Renee R Hood, Don L. DeVoe
Abstract: Here we report a microfluidic system that enables rapid and efficient remote loading of amphipathic drugs into nanoscale liposomes, combining liposome synthesis and remote drug loading in a continuous integrated process. Unlike established bulk m ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915563

5. A Facile Route to the Synthesis of Monodisperse Nanoscale Liposomes Using 3D Microfluidic Hydrodynamic Focusing in a Concentric Capillary Array
Topic: Drugs/Pharmaceuticals
Published: 5/14/2014
Authors: Wyatt N Vreeland, Renee R Hood, Don L. DeVoe, Francisco Javier Atencia, Donna M. Omiatek
Abstract: A novel microscale device has been developed to enable the one-step continuous flow assembly of monodisperse nanoscale liposomes using three-dimensional microfluidic hydrodynamic focusing (3D-MHF) in a radially symmetric capillary array. The 3D-M ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915562

6. Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram
Topic: Drugs/Pharmaceuticals
Published: 4/11/2014
Authors: Andrey Galkin, Liudmila Kulakova, Kap Lim, Catherine Chen, Wei Zhang, Illarion V Turko, Osnat Herzberg
Abstract: Carbamate kinase from Giardia lamblia is an essential enzyme for the survival of the organism. The enzyme catalyzes the final step in the arginine dihydrolase pathway converting ADP and carbamoyl phosphate to ATP and carbamate. We previously repo ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915235

7. Microfluidic-Enabled of Liposomes Elucidate Size-Dependent Transdermal Transport
Topic: Drugs/Pharmaceuticals
Published: 3/21/2014
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Don L. DeVoe, Julia Finkel, Mariana Junqueira, Zenaide Quezado
Abstract: Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915017

8. Facile Smiles-type rearrangement in radical cations of N-acyl arylsulfonamides and analogs
Topic: Drugs/Pharmaceuticals
Published: 1/21/2014
Authors: Karl K Irikura, Nino Guram Todua
Abstract: RATIONALE: N-Alkylation of sulfonylbenzamides was reported recently to cause a dramatic and surprising change in electron ionization mass spectrometry (EIMS), leading to a closed-shell base peak. Only an incomplete, speculative mechanism was availabl ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912656

9. Determining carbapenemase activity with 18O labeling and targeted mass spectrometry
Topic: Drugs/Pharmaceuticals
Published: 10/16/2013
Authors: Meiyao Wang, Yang Shen, Illarion V Turko, Daniel Nelson, Shuwei Li
Abstract: Carbapenems are broad spectrum antibiotics considered as last resort drugs to treat bacterial infections. Carbapenem-hydrolyzing β-lactamases (also called carbapenemases), however, can confer bacterial resistance and represent a serious health t ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914525

10. Microfluidic preparation of liposomes to determine particle size influence on cellular uptake mechanisms
Topic: Drugs/Pharmaceuticals
Published: 10/3/2013
Authors: Wyatt N Vreeland, Abhay U Andar, Renee R Hood, Don L. DeVoe, Peter W Swaan
Abstract: Purpose: This study investigates the cellular uptake and trafficking of liposomes in Caco-2 cells, using vesicles with distinct average diameters ranging from 40 nm-276 nm. Liposomes were prepared by microfluidic hydrodynamic flow focusing, producing ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913538



Search NIST-wide:


(Search abstract and keywords)


Last Name:
First Name:







Special Publications:

Looking for a NIST Special Publication (NIST SP Series)? Place the series number and dash in the report number field (Example: 800-) and begin your search.

  • SP 250-XX: Calibration Services
  • SP 260-XX: Standard Reference Materials
  • SP 300-XX: Precision Measurement and Calibration
  • SP 400-XX: Semiconductor Measurement Technology
  • SP 480-XX: Law Enforcement Technology
  • SP 500-XX: Computer Systems Technology
  • SP 700-XX: Industrial Measurement Series
  • SP 800-XX: Computer Security Series
  • SP 823-XX: Integrated Services Digital Network Series