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You searched on: Topic Area: Life Sciences Research

Displaying records 1 to 10 of 145 records.
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1. Quantitative scheme for full-field polarization rotating fluorescence microscopy (PROM) using a liquid crystal variable retarder
Topic: Life Sciences Research
Published: 5/14/2015
Authors: John F. Lesoine, Ji Y. Lee, Hyeong Gon Kang, Matthew Lawrence Clarke, Robert C. Chang, Ralph Nossal, Jeeseong Hwang
Abstract: We introduce real-time, full-field, polarization rotating fluorescence microscopy (PROM) to monitor the absorption dipole orientations of fluorescent molecules. A quarter-wave plate, in combination with a liquid crystal variable retarder (LCVR ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908548

2. Validated Open Source Nanofiber Diameter Measurement Tool
Topic: Life Sciences Research
Published: 4/30/2015
Authors: Nathan A Hotaling, Kapil Bharti, Haydn Kriel, Carl George Simon Jr.
Abstract: Despite the growing use of nanofiber scaffolds for tissue engineering applications, there is not a validated, readily available (commercial or open source) solution for rapid, automated analysis of nanofiber diameter from scanning electron microscope ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=917542

3. Quantitative Mass Spectrometry Measurements Reveal Stoichiometry of Principal Postsynaptic Density Protein Components
Topic: Life Sciences Research
Published: 4/28/2015
Authors: Mark S Lowenthal, Sanford Philip Markey, Ayse Dosemeci
Abstract: Quantitative studies are presented of postsynaptic density (PSD) fractions from rat cerebral cortex with the ultimate goal of defining the average copy numbers of proteins in the PSD complex. Highly specific and selective isotope dilution mass spectr ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=917230

4. The Art in Science of MicroTAS: the 2014 issue
Topic: Life Sciences Research
Published: 4/14/2015
Author: Darwin R Reyes-Hernandez
Abstract: For the 7th year in a row the Art in Science award competition, sponsored by Lab on a Chip and the National Institute of Standards and Technology (NIST), took place at the 18th International Conference of Miniaturized Systems for Chemistry and Life S ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=918292

5. Application of NMR-based Metabolomics for Environmental Assessment in the Great Lakes using Zebra Mussel (Dreissena polymorpha) polymorpha)
Topic: Life Sciences Research
Published: 2/21/2015
Authors: Miki Watanabe, Katherine Meyer, Tyler Jackson, Tracey Beth Schock Schock, Ed Johnson, Daniel W Bearden
Abstract: Zebra mussel, Dreissena polymorpha, in the Great Lakes is being monitored as a bio-indicator organism for environmental health effects by the National Oceanic and Atmospheric Administration‰s Mussel Watch program. In order to monitor the enviro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916464

6. Rbm24a and Rbm24b are required for normal somitogenesis
Topic: Life Sciences Research
Published: 8/29/2014
Author: Samantha D Maragh
Abstract: We recently demonstrated that the gene encoding the RNA binding motif protein 24 (Rbm24)¬¬ is expressed during mouse cardiogenesis, and determined the developmental requirement for its zebrafish homologs Rbm24a and Rbm24b during cardiac developme ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915918

7. Polyelectrolyte Multilayers in Microfluidic Systems for Biological Applications
Topic: Life Sciences Research
Published: 7/31/2014
Authors: Saugandhika Sarma Minnikanti, Aveek Gangopadhyay, Darwin R Reyes-Hernandez
Abstract: The formation of polyelectrolyte multilayers (PEMs) for the first time two decades ago demonstrating the assembly on charged substrates in a very simple and efficient way have proven to be a reliable method to obtain structures tunable at the nanomet ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916103

8. Machine Learning Analysis for Identification of Cell Shape Metrics Associated with Stem Cell Differentiation in Nanofiber Scaffolds
Topic: Life Sciences Research
Published: 4/19/2014
Authors: Desu Chen, Sumona Sarkar, Stephen J Florczyk, Subhadip Bodhak, Carl George Simon Jr., Joy P Dunkers, Julian Candia, Wolfgang Losert
Abstract: Cell shape has been demonstrated to be closely related to cell function and may be an important predictor of cell fate. Many metrics are available to describe cell shape, however the relationship of these metrics to cell fate are not well understood ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914971

9. Roles of Nanofiber Structure and Chemistry in Directing Stem Cell Morphology, Differentiation and Gene Expression
Topic: Life Sciences Research
Published: 4/19/2014
Authors: Sumona Sarkar, Bryan A. Baker, Desu Chen, Wolfgang Losert, Carl George Simon Jr., Joy P Dunkers
Abstract: Nanofiber technology has emerged as a promising tool to recapitulate the native extracellular matrix (ECM) environment for tissue engineering and regenerative medicine strategies. Cell-material interactions in the nanofiber system are largely de ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914988

10. Why human genome sequencing platforms differ: Integrating sequencing datasets to understand biases and form consensus variant calls
Topic: Life Sciences Research
Published: 2/16/2014
Authors: Justin M Zook, Brad Chapman, Winston Hide, Marc L Salit
Abstract: Hundreds of thousands of differences exist between human whole genome variant calls from different sequencing platforms and variant calling pipelines, but the reasons for these differences are poorly understood. Well-characterized whole genome Refer ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912658



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