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Bioscience

Cell-free systems

The Research

cell free assay plate with notional data

Assay Development for Cell-Free Expression Systems

Ongoing
Current practices for characterizing cell-free expression systems are limited and unsuitable to advance these technologies beyond the state-of-the-art. To meet this measurement need, the Cellular Engineering Group is developing quantitative assays to benchmark cell extracts, reagents, and cell-free
ctRSD toolkit overview

RNA Computation and Metrology for Engineering Biology

Ongoing
RNA computation RNA computation, i.e., programmed interactions between RNA molecules that process information, is an increasingly useful synthetic biology tool with applications spanning in vitro biosensing, synthetic cells, and cellular control. We have developed cotranscriptionally encoded RNA
Gears illustrating NIST's cell-free systems initiatives

Metrology For Cell-Free Expression Systems

Ongoing
Cell-free expression systems are poised to advance the US bioeconomy and play a key role in ensuring US manufacturing resilience. NIST has several, on-going projects in its growing portfolio to promote reproducibility, new measurement methods, and best practices and standards in cell-free expression

News and Updates

A fire burns along the ground at the edge of a wooded area.

NIST Awards More Than $4 Million to Small Businesses for Innovations in AI, Wildfire Forecasting and More

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Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green.

NIST and Frederick National Laboratory for Cancer Research Help Ensure Accurate Clinical Measurements of HER2 Breast Cancer Gene

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Photo of deer tick

New Experimental Test Detects Signs of Lyme Disease Near Time of Infection

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