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Projects/Programs

Displaying 1 - 14 of 14

Advanced Magnetic Imaging

Ongoing
Ultra-low field (ULF) MRI MRI systems are widely used for clinical diagnostics where imaging is typically done in high-field magnets ranging from 1.5 T to 7 T to achieve a manageable signal-to-noise ratio needed for short imaging times (few minutes) and high resolution (1 mm or less). Ultra-low

Cell-based Assay for Mechanistically-based Prediction of Cytoxicity

Completed
Ricin is a type 2 ribosome inactivating protein (RIP) belonging to the A-B family of toxins and is of particular interest because of its potential use as a biological weapon and the dearth of rapid and sensitive assays that could assist detection and decontamination. The ricin toxin inhibits protein

Hyperspectral Image Projector (HIP)

Ongoing
Remote sensing instruments and medical imagers are designed to take images composed of many spectral bands, not just the minimum three components used by common digital cameras (i.e., red, green, and blue). These images are referred to as hyperspectral because each pixel contains information for

Magnetic Sensing and Metrology

Ongoing
Magnetic sensors have a wide range of sensitivities, spatial resolution, dynamic range, bandwidths, size, and cost. Applications such as magnetic data storage and chip NDE require sensitivity of 1 nT, spatial resolution down to a few nanometers and bandwidths up to 10 GHz, while MEG requires

Nano-biophotonics for molecular imaging

Ongoing
Nano-biophotonics consists of four broad areas: molecular bioimaging; nano-biosensors; multiplexed bioassays ; and nanotechnology-based medical practices for diagnosis and therapy. Success in these areas is challenged by the underlying complexity of biological systems. Major levels of complexity and

Optical Medical Imaging

Ongoing
We advance measurement science and standards infrastructure to accelerate adoption of optical medical imaging technologies for surgical and clinical applications. Optical medical imaging promises to enhance and complement conventional medical imaging modalities that include magnetic resonance

Optical medical imaging

Optical medical imaging technologies proliferate in academic research and yet very few translate into the clinic. Optical techniques have high spatial and spectral resolution, lends itself to portability, and inexpensive relative to conventional imaging modalities such as MRI (Magnetic Resonance

Photonic Dosimetry

Ongoing
With this effort, NIST is responding to industry needs for traceable, measurement solutions that can resolve spatial variations of absorbed dose at the level of individual components on a silicon wafer or bacteria on surgical instruments. Presently, there is only limited traceability to national

Quantitative MRI

Ongoing
Future directions may focus on multimodal imaging, techniques that use MRI as either a base or as a complimentary technique. Multimodal imaging combines information from two or more imaging modalities such as MRI, computed tomography (CT), positron emission tomography (PET), and ultrasound (US)

Reflectance Measurements of Human Skin

Ongoing
Investigations of the optical properties of human skin have largely been limited to the visible part of the electromagnetic spectrum, whereas many applications require high-quality reflectance data in the near infrared and short-wave infrared. Further, the complex and dynamic nature of skin results

SMART Contrast Agents

Ongoing
Work on smart agents is focused on developing new micro- and nanoparticle- based contrast agents for MRI and new MR imaging and sensing schemes. These include synthetic antiferromagnet nanoparticles as potential new contrast agents, high-moment iron microparticles for enhanced T2* contrast for in

X-ray computed tomography (CT) for medical applications

Completed
As scale lengths get smaller, diffraction becomes increasingly prominent in tomography. The work here develops diffraction tomography for laboratory sources. A new laboratory scale instrument at NIST/Boulder is dedicated to tomography of integrated circuit interconnects. Tomography software written