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Projects/Programs

Displaying 1 - 17 of 17

Advanced Materials Metrology

Ongoing
Electromagnetic devices cannot operate without the interaction of electromagnetic waves with materials, and the characterization of the interface between fields and materials will be a critical task for any device or metrology development from nanoscale to larger scales. Areas of impact over the

Computational Scanning Electron Microscopy

Ongoing
In many cases, SEM measurements are carried out without knowledge of the best measurement conditions, partly due to engineering limits of the SEM, but also due to lack of thorough knowledge of the physics of the signal generation. For example, in many cases the best-quality results can be obtained

DNA Origami for Precise Manufacturing of Nanoscale Structures

Completed
The base pairing of adenine to thymine and guanine to cytosine to form DNA provides a robust molecular recognition scheme that can be used to create a wide variety of well-ordered nanostructures. DNA origami, which uses a long scaffold strand folded together by specific sets of short staple strands

Fluctuations and Nanoscale Control Software (Archived)

Completed
For each file YYY.m, type "doc YYY" from the Matlab command prompt for documentation, literature references, and usage guidelines. DSigma2_Est.m Estimates the diffusion coefficient (D) and localization noise (σ 2 or "Sigma2") from single-particle tracking data. It implements the algorithms for the

Measurements for minimal cells

Ongoing
Minimal cells are cells whose genome has been stripped of all but those genes essential for replication, in a process called "genome minimization." NIST and collaborators demonstrated genome minimization coupled to single cell imaging as a powerful approach to investigate the minimal genetic

Micro- and Nanoelectromechanical Systems

Completed
MEMS/NEMS are enabling technologies that bring new functionalities with the potential to radically transform markets ranging from consumer products to national defense. The meteoric rise of the smartphone is an excellent example, in which MEMS accelerometers, gyroscopes, microphones, displays, and

Micro-rheometry

Completed
One way to develop small-volume rheology methods that we have used successfully is to start with existing concepts and geometries of rheometry and to then "think small." This approach ensures that we are measuring fundamental materials properties rather than quantities that are experiment and

Molecular Physiology

Ongoing
In close collaboration with experimentalists, we are seeking to increase the resolution, scope, and throughput of single-biomolecule and ensemble techniques, such as nanopore-based biomolecular analysis, ultrafast vibrational spectroscopy, and FRET, among others. These developments rely heavily on

Nanomagnet Dynamics

Ongoing
The motion of the magnetization in magnetic nanostructures is at the core of important technologies such as computer hard drives and magnetic memory chips. Additionally, emerging technologies such as magnetic logic and second-generation spin-torque memory chips write and read "bits" of information

Nanoparticle Tracking for Fluidic Self Assembly (Archived)

Completed
Over the last few decades, scientists have developed a sizable library of nanoscale "building blocks." These nanoparticles have novel thermal, optical, mechanical, and chemical properties relative to their macroscopic counterparts, and organized assemblies of these components promise vast

Sensing, Transport, and Simulation

Ongoing
We have recently developed a finite-size scaling approach and special simulation cell aspect ratio—the golden aspect ratio—to enable accurate incorporation of access resistant and bulk diffusion in ionic transport, see the figure. This enables quantitative, and efficient, prediction of ion transport