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Physics

Projects/Programs

Keyword

Organizational Unit

International System of Units (SI)

Ongoing

Members of the Fundamental Constants Data Center (FCDC) participate in meetings of the Consultative Committee for Units (CCU) which advises the International Committee for Weights and Measures on matters concerning the SI. The latest meeting of the CCU, held at the BIPM in June of 2013 was attended

A chart showing the various sectors served by the Laser Power & Energy Meter calibrations project as of 2025

Laser Power and Energy Meter Calibrations

Ongoing

We serve Industry, DoD, and research institutions by calibrating instruments used to measure the power or energy emitted by a laser, or single photon source. From Single Photons to Kilowatts, Longwave Infrared to Deep Ultraviolet, Free-space and Fiber, we can calibrate your instruments. The chart to

Light-matter interactions in Semiconductor Nanostructures

Ongoing

We investigate the interaction of light with semiconductor-based nanostructures. We extend concepts of entanglement and coherence in atomic physics to our solid-state systems. Our devices are based on semiconductors, like GaAs. We use InAs quantum dots (QDs) in GaAs as artificial atoms; they have

5 MHz Graph of phase noise vs. offset frequency showing NIST synthesized signal, Wenzel OXCO, and BVA oscilloquartz.

Low-Phase Noise Frequency Synthesis

Ongoing

Frequency synthesis plays an essential role in virtually all present-day commercial, industrial, and military technologies. State-of-the-art low-noise frequency synthesis is a crucial technical asset to high-resolution imaging and radar, high-speed telecommunications, and efficient management of the

Machine Learning Fluid Equations of State

Ongoing

Understanding the thermodynamic properties of fluids and fluid mixtures is of central importance in many fields of science and engineering ranging from medicine to consumer products. The nature of the particles in a fluid can vary greatly depending on the type of interactions present, e.g., dipole

Magnetic Sensing and Metrology

Ongoing

Magnetic sensors have a wide range of sensitivities, spatial resolution, dynamic range, bandwidths, size, and cost. Applications such as magnetic data storage and chip NDE require sensitivity of 1 nT, spatial resolution down to a few nanometers and bandwidths up to 10 GHz, while MEG requires

Medical (Archive): Calibration of Epoxy Based Ba-133 Standard Phantom Sources for Use in an International Comparison for Quantitative SPECT

Completed

One of the early goals of the CRP is to assess the global state of the accuracy and consistency of Single Photon Emission Tomography (SPECT) image quantification, as evidenced by the performance of the institutions participating in the project during a series of comparison exercises. Based on

Medical (Archive): Calibrations of Large-Volume, Solid Ge-68 Phantom Sources for Monitoring PET Scanner Performance in Clinical Trials

Completed

Although the data from most PET studies are often used on a relative basis, the quality of the analysis will be greatly improved if the data can be normalized using a common reference standard that allows instrumental variability to be minimized. This requires long-lived PET phantoms to be available

Medical (Archive): Small-field Therapy Dosimetry Studies Using Alanine/EPR

Completed

Developments in radiotherapy have significantly increased the use of small fields in stereotactic procedures and IMRT fields composed of small fields. Ionization chambers are not always suitable where situations of high dose gradients, time-dose variance, and non-uniform beam distributions are

Medical (Archive): Workshop for Radiobiology Dosimetry Standardization

Completed

Workshop Agenda with Presentations RADIATION DOSE IS MORE THAN A NUMBER! National Institute of Standards and Technology 100 Bureau Drive, Gaithersburg, MD Green Auditorium September 15 and 16, 2011 THURSDAY, SEPTEMBER 15, 2011 Welcome and Introduction Lisa Karam, NIST Bert Maidment, NIAID Norm

Medical: Characterization of Dosimeters Used in Computed Tomography

Completed

The Dosimetry Group of the Radiation Physics Division has an on-going collaboration with the FDA, NIH, and the Walter Reed National Military Medical Center to characterize clinical dosimeters for the purpose of monitoring the radiation dose delivered to patients during computed tomography (CT) exams

Medical: Printed 2D phantoms with traceable activity for autoradiography calibrations

Ongoing

Exciting advances in precision cancer therapy use chemical targeting to deliver alpha-emitting radionuclides to tumor sites. There, the high energy and short range of alpha particles means the tumor is killed while neighboring healthy tissue is spared. This is targeted alpha therapy (TAT). While the

Medical: Standards for Clinical Radionuclide Calibrators

Ongoing

In nuclear medicine, clinical activity measurements are typically made using commercially available radionuclide calibrators (also referred to as “dose calibrators”) which incorporate a reentrant 4π ionization chamber and an electrometer. The current measured by these calibrators is translated into

Metrologies for Protein Structure, Dynamics and Function

Ongoing

Based on its established expertise, infrastructure, and resources for structure/function studies of biological macromolecules, the program aims to impact advances in physics, chemistry, and engineering relevant to biological problems. NIST researchers also develop new technologies for application to

Metrology for extreme ultraviolet lithography

Ongoing

Patterning with light 13 nm brings a host a new challenges Light at 13 nm is well within the vacuum ultraviolet, where radiation is strongly absorbed by all materials. This requires that the technology take place in vacuum and rely on mirrors rather than lenses. Moreover generating sufficient

Micro- and nano-optomechanical systems

Ongoing

Our primary current research direction involves the use of fabricated devices with sub-wavelength periodicity (photonic crystals) as optomechanical elements. Such structures enable a rich variety of devices, including mirrors, polarizers, and filters, in a configuration that couples naturally to

Microresonator frequency combs for the NIST-on-a-Chip Program

Ongoing

The invention of optical-frequency combs opened many new applications in photonics from precision timing and ranging to generation of entangled states. They are composed of hundreds to millions of optical modes whose frequencies conform to a simple relationship, ν n = n × f rep +f 0, where n is the

Microresonators for inductive-detection electron paramagnetic resonance spectroscopy of volume-limited samples

Ongoing

Spin-detection in volume-limited samples has applications ranging from solid-state physics to structural biology. Increasingly, technologically-relevant materials have nanoscale dimensions. Single microcrystals may only have volumes ranging from picoliters to nanoliters. Many biological materials

Molecular Physiology

Ongoing

In close collaboration with experimentalists, we are seeking to increase the resolution, scope, and throughput of single-biomolecule and ensemble techniques, such as nanopore-based biomolecular analysis, ultrafast vibrational spectroscopy, and FRET, among others. These developments rely heavily on

Nanoscale Spectroscopy for Advanced Electronics, Quantum Materials and Devices

Ongoing

Semiconductor technologies are critical to U.S. economic and national security as they are essential to modern life in communications, healthcare, energy, etc. and also underpin many emerging technologies like quantum, artificial intelligence, high power electronics and advanced wireless (6G+). The

A scanning electron micrograph of a QDOGFET device used for photon number-resolving detection.

Nanostructure Fabrication and Metrology

Completed

This project develops semiconductor nanostructures, especially self-assembled quantum dots and photonic crystals, for a variety of applications including single photonics, laser diodes, and quantum optical metrology. It also develops quantum optical metrology based on other sources and detectors

National Type Evaluation Program (NTEP)

Ongoing

NTEP requires industry to submit prototype weighing devices for evaluation to determine whether or not it meets the uncertainties which are related to tolerances associated with the intended final use in the marketplace. All devices sold in the United States for "legal for trade" purposes must pass

New Reference Standards for Digital Mammography

Ongoing

These beams will provide FDA inspectors, ionization chamber manufacturers, and calibration facilities with the spectra that best represent what is used in clinics. These new reference radiation techniques will be available for calibrations and the FDA-MQSA proficiency tests. The beam parameters are

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Newtonian constant of gravitation international consortium

Ongoing

The disagreement calls into question our ability to measure small forces on a laboratory scale. It also raises the question of whether the Newtonian force law is a complete description of gravity at these distances. An international consortium is being formed to address this problem. The

Evolution of Flat-histogram Monte Carlo Simulation

NIST Standard Reference Simulation Website

Ongoing

Molecular simulations, in particular Monte Carlo Molecular Simulation and Molecular Dynamics Simulation, are methods for computing the properties of some kind of system, for which the intermolecular interactions are specified via mathematical relationships derived from statistical mechanics. Since

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