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Standards

Reference materials

News and Updates

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SRM 915c Calcium Carbonate Mass Fraction Standard

January 18, 2023

This standard reference material from NIST will help calibrate procedures for calcium determinations used in clinical analysis and for routine critical

A gloved hand holds a glass flask partly full of pinkish liquid, with a label in marker saying in part "NISTCHO RCB."

NIST, Partners Develop Living Reference Material for Producing Monoclonal Antibodies

January 11, 2023

Publicly available NISTCHO cell line expands the biomanufacturing and research applications of NIST’s monoclonal antibody standard, NISTmAb.

NIST Develops Yeast Material for Training First Responders on Biothreats

January 4, 2023

Researchers based the material on baker’s yeast because it is harmless and a living biological material.

What is a Standard Reference Material?

November 28, 2022

https://www.nist.gov/video/what-standard-reference-material-or-srm.

NIST Issues the First Standard Reference Material for the Quantitative Analysis of Glycans

August 3, 2022

NIST Standard Reference Material (SRM) 3655 helps biopharmaceutical manufacturers perform measurements of glycan molecules in their protein drug products

Picture of jars containing reference materials 8256, 8257, 8258, and 8259: Wild caught and aquacultured shrimp and salmon

Four NIST Reference Materials Help Authenticate Shrimp and Salmon

July 28, 2022

Four reference materials from NIST will help the U.S. Food and Drug Administration and Customs and Border Protection agencies assess whether imported salmon and

A gloved hand is holding up a small plastic vial labeled "RGTM plasmid."

NIST Develops Genetic Material for Validating Mpox Tests

July 27, 2022

NIST is making the new material freely available to testing laboratories and diagnostic test manufacturers worldwide.

a picture of packaging for NIST SRM 2367JC Virus DNA Quantitative Standard

A NIST Standard for More Accurate Diagnoses of JC Virus

July 19, 2022

A new NIST Standard Reference Material supports the accurate measurement of the amount of a common but potentially dangerous virus in patients. Most of us have

Petri dish holds brown material with several different types of circular microbes.

Spotlight: Going With the Gut for the Future of Health

June 27, 2022

NIST researchers are developing a human gut microbiome reference material.

Two open glass containers hold powder, one brown and one wite, with half-filled plastic scoops next to each.

NIST Tree Nut Reference Materials Support Food Allergen Testing

June 6, 2022

Researchers from NIST have developed hazelnut and almond flour reference materials that will help ensure accurate and consistent results for industry test kits.

Measuring Up: The Phantom of the Library

May 4, 2022

Magnetic resonance imaging (MRI) has revolutionized medical diagnostics and research by providing a non-invasive way to investigate internal tissue structures

NIST Produces Complete Suite of Supports for Testing for Allergens in Food

April 25, 2022

With the addition of two new reference materials containing tree nuts, NIST now offers a complete set of aids for detecting allergens in food. As of 2022, the U

NIST Supports Accurate Food Labeling with New Standard Reference Material for Fat

April 20, 2022

NIST Standard Reference Material® 2386 Avocado Powder helps food manufacturers evaluate their methods for determining the elements, vitamins, amino acids, fatty

NIST Supports Measurements of Vitamins in Dietary Supplement Tablets

April 14, 2022

NIST Standard Reference Material ® 3289 Multivitamin Tablets will be used by testing laboratories to support the development of new analytical methods that

An open black box with foam inserts holds plastic vials labeled SRM 2917.

NIST Collaborates With EPA to Develop a Standard to Improve Fecal Pollution Measurements in Recreational Waters

April 6, 2022

As we approach summer beach season, you may occasionally encounter a "keep out" sign indicating that the area is temporarily closed. If fecal pollution is

New Benchmark Could Improve Detection of Genetic Variants Linked to Spinal Muscular Atrophy, Other Diseases

February 7, 2022

The stretches of DNA that differ from person to person, called variants, are a major part of what makes us unique, but they can also put us at greater risk of

Suite of NIST Reference Materials Reflects Supply Chain and Production Stages of Ginseng Supplements

January 25, 2022

Three NIST reference materials of ginseng in different forms support ginseng supplement manufacturers’ analysis of the authenticity and purity of their products

Megan Cleveland with white lab coat and safety glasses in front of a lab bench with pipettes.

RNA Reference Materials Are Useful for Standardizing COVID-19 Tests, Study Shows

January 20, 2022

Scientists track and monitor the circulation of SARS-CoV-2, the virus that causes COVID-19, using methods based on a laboratory technique called polymerase

NIST Standard Reference Material Supports Clinical Tests for Common Chronic Diseases

December 20, 2021

NIST has developed its first reference material to aid in the measurement of free fatty acids in human blood serum. Most adults who routinely monitor their

A researcher stands on a boat reaching for a cable holding a grabber device.

NIST Releases Great Lakes Sediment Material for Measuring Organic Pollutants

November 23, 2021

People who live near the Great Lakes might go there to enjoy a swim or a boat ride. But if you’re visiting from the National Institute of Standards and

Yellowish blades of kelp are growing under the surface of the water.

Spotlight: Harvesting What's Under the Sea for the Dietary Supplement Industry and Environmental Conservation

November 16, 2021

From domestic sludge to hydrogen in titanium, we have many different types of standard reference materials (SRMs) to ensure that industry, academia and

New NIST Reference Material Helps Manufacturers Better Assess Their Biological Drug Products

November 15, 2021

Sugars not only provide nourishment in the food you eat but can also act as biomarkers for detecting disease. When certain types of simple sugars, such as

NIST pH Standard Reference Material Supports One of Manufacturing’s Most Measured Properties

October 19, 2021

NIST has released a pH reference material in a uniquely stable form for calibrating the instruments used by a wide variety of manufacturers. pH is one of the

Spotlight: Tracking Methylmercury, a Toxic Substance in Natural Waters

August 16, 2021

Mercury — the only metal that exists in liquid form at room temperature — may move like water, but its effect on the environment certainly isn’t replenishing

NIST Reference Material for Hydrogen in Titanium Now in Pin Form

August 16, 2021

Hydrogen in titanium and other metal alloys can cause embrittlement, leading to fractures in manufactured parts. A popular NIST reference material for

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