The team pioneered measurement and control techniques and validated the quantum mechanical entanglement of two macroscopic mechanical resonators, with masses on the order of tens of picograms (10^12 atoms). This work experimentally tested the physical size limits at which quantum mechanics ends and classical physics begins. In addition to the impact on basic physics, the techniques demonstrated in this experiment may find application in continuous-variable quantum computing schemes, where fast entangling operations are as critical as logic gates.