The team is recognized for the invention of serial cytometry, aiding in clinical decision-making by enabling early cancer identification and tracking of residual disease through rare-cell detection. Serial cytometry sets a new standard for the quantitative evaluation of cellular response to therapeutics. The team's achievements enable rigorous single-cell measurements, removing a longstanding hindrance to robust medical diagnostics and providing the first-ever real-time dynamic measurements of cellular functions, including signaling and metabolism.