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Next-Generation MRIs

Breast cancer MRI phantom
NIST engineer Katy Keenan holds a "phantom" that is used to standardize magnetic resonance imaging (MRI) of the breast. This phantom mimics the response of human breast tissue to test the performance of MRI systems.
Credit: von Dauster/NIST

Conventional magnetic resonance imaging (MRI) machines help doctors diagnose a range of diseases, from brain tumors to bone deficiencies, but in common use, they only provide qualitative information. In other words, they merely display differences between adjacent areas. 

More valuable information is available if we collect and analyze those images quantitatively — providing measurements of those differences. To support these quantitative analyses, NIST has developed measurement “phantoms” — objects with carefully measured properties that mimic human tissue and can be used to calibrate MRI systems or support research. 

NIST maintains a lending library that enables quantitative MRI research for improving health outcomes. Recent studies show that with quantitative MRI, glioblastoma patients could learn if a particular treatment works for them within days, allowing for rapid adjustment of a treatment regimen. While research continues, doctors believe that quantitative MRI could improve the diagnosis of other diseases, such as stroke, dystrophy and a range of cancers.

Learn more about imaging phantoms

Related video

NIST Phantoms
NIST Phantoms
The word “phantom” may conjure up scary ideas, like ghosts or delusions. But phantoms are also useful scientific devices. In the biomedical research community, medical imaging phantoms are objects used as stand-ins for human tissues to ensure that systems and methods for imaging the human body are operating correctly. NIST develops and disseminates phantoms as part of an ongoing effort to help ensure that medical images provide reliable and quantitative (measurable) information, not just nice pictures. Find out more about NIST's phantom work.
Created March 17, 2025, Updated March 21, 2025