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Reliable Vaccine Storage

Alex Rodriguez with data logger

Alexandra Rodriguez demonstrating the broken contact style of data logger.

The United States invests billions of dollars in vaccine manufacturing and distribution. However, if vaccines are exposed to inappropriate temperatures, they can lose their potency. To avoid wasteful spending and modern-day outbreaks of vaccine-preventable diseases, failures in the “cold chain” (vaccine storage and delivery) must be prevented. 

Between 2009 and 2022, NIST conducted a comprehensive study of temperature control for vaccine storage and transport and developed best-practice guidance for public health stakeholders. As a result of the program, certain refrigerator designs and data-logging methods were identified as ineffective. 

NIST’s work led to a significant reduction in vaccine waste — more than 30% in some instances. NIST’s renowned technical expertise and commitment to scientific integrity led to the establishment of the first-ever standards for vaccine storage. These standards represent a resounding success that will continue to benefit the nation long after the completion of the study.

Learn more about the reliable vaccine storage program

Created March 17, 2025, Updated March 21, 2025