Lambertian nature of tissue phantoms for use as calibrators in near infrared fluorescence imaging

Published

March 9, 2016

Author(s)

Maritoni Litorja, Simon Lorenzo, Banghe Zhu, Eva Sevick Muraca

Abstract

The use of tissue phantoms as calibrators to transfer SI-referenced scale to an imager offers convenience, compared to other methods of calibration. The tissue phantoms are calibrated separately for radiance at emission wavelength per irradiance at excitation wavelength. This calibration is only performed at a single geometric configuration, typically with the detector normal to the sample. In the clinic however, the imager can be moved around, resulting in a geometric configuration different from the calibration configuration. In this study, radiometric measurements are made at different sample-imager angles to test whether the tissue phantoms are Lambertian and the angular limits to which the calibration values hold true.

Volume

9696

Conference Dates

February 12-18, 2016

Conference Location

San Francisco, CA, US

Conference Title

Molecular-Guided Surgery: Molecules, Devices, and Applications II (Conference 9696)

Pub Type

Conferences

Download Paper

https://doi.org/10.1117/12.2216324

Local Download

Keywords

near infrared fluorescence imaging, molecular imaging, radiometry, calibration, tissue phantoms

Citation

Litorja, M. , Lorenzo, S. , Zhu, B. and Sevick Muraca, E. (2016), Lambertian nature of tissue phantoms for use as calibrators in near infrared fluorescence imaging, Molecular-Guided Surgery: Molecules, Devices, and Applications II (Conference 9696), San Francisco, CA, US, [online], https://doi.org/10.1117/12.2216324, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=920479 (Accessed October 10, 2025)