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EVENTS

Genome Editing Consortium Workshop

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Genome editing technologies

The purpose of this workshop is to share and obtain feedback on current and future activities of the NIST Genome Editing Consortium. Discussion topics will include control materials/assay qualification for DNA detection, genome editing data/metadata norms, and newly launched sub-groups focused on controls for and qualification of off-target assays, and quality of genome editing components.

 

9:00 am – 9:10 am 

Welcome & Opening Remarks 

Workshop Overview 

9:10 - 10:10 am 

Update from Federal Partners with related efforts  

10:10 – 10:30 pm 

Coffee Break 

10:30 – 12:00 pm 

Update on Current NIST Genome Editing Consortium Activities and discussion of next steps  

  • WG1 Specificity Measurements:  DNA- and cell-based control materials and interlab analysis

    • Updates on first interlab study and progress towards pilot engineered cell lines

  • WG1-subgroup: Quality of genome editing components 

    •  Subgroup Objective: Identify sources of variability and develop consensus approaches to qualifying off-target assays (including potential interlaboratory studies or control materials)

  • WG1- subgroup: Qualification of off-target assays 

    •  Subgroup Objective: Identify concepts/information, approaches/assays, and potential controls for assessing quality of genome editing components

  • WG3 Lexicon:  ISO 5058 Genome Editing Part 1 Vocabulary; next steps for Lexicon and additional terms to consider 

12:00 – 1:00 pm 

Lunch Break 

1:00 – 3:00 pm  

Breakout Topics 

  • Off-target genome editing: Data analysis, data interpretation, and metadata 

  • Measurement Challenges for Epigenetic Editors 

3:00 – 3:20 pm 

Coffee Break 

3:20 – 4:40 pm  

Technology Talks (10 mins each)

  • Countagen AB 

  • E9 Genomics, Inc. 

  • seqWell, Inc. 

  • Edilytics, Inc. 

  • Additional speakers TBA

4:40 – 5:00 pm  

Re-cap of workshop & adjourn  

Bioscience, Bioinformatics, Genome editing, Health, Biopharmaceuticals, Cell and gene therapy, Precision medicine and Regenerative medicine and advanced therapy
Created November 6, 2024, Updated February 7, 2025