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Material Measurement Laboratory /Chemical Sciences Division

Organic Chemical Metrology Group

The Organic Chemical Metrology Group is responsible for developing, critically evaluating, and applying liquid chromatographic, gas chromatographic, spectroscopic and mass spectrometric techniques for the confident identification and measurement of organic species in a variety of matrices.

About

The Organic Chemical Metrology Group (OCMG) develops, critically evaluates, and applies analytical methods based on liquid chromatography, gas chromatography, high-resolution mass spectrometry, multidimensional chromatographic separation procedures, vibrational and nuclear magnetic resonance spectroscopy, as related to analyses at trace and ultratrace concentration levels.  The OCMG designs, produces and maintains an extensive portfolio of Standard Reference Materials and data products, primary standards, and Quality Assurance programs for organic species in clinical, nutritional assessment and metabolomics, food safety and nutrition, dietary supplement and natural products, chemical manufacturing, and forensics program areas. The group provides advice and measurement services to other government agencies, scientific organizations, and US industry; and engages with international standards organizations and other National Metrology Institutes (NMIs) to establish comparability of measurement capabilities.

SELECT FOCUS AREAS

Illustration consisting of a multicolored triangle divided into 9 sectors with different levels of fat, protein and carbohydrates, and with various types of foods indicated for each sector.
Measurements and Standards to Support Nutrition Labeling
Word cloud featuring “Quality Assurance”
Clinical Measurements Quality Assurance Program
Photograph of ginkgo leaves with overlayed chromatogram labeled with ginkolide designations.
Measurements and Standards for Botanical Dietary Supplements

News and Updates

RMs 8690 to 8693

Standards for Tracking PFAS Contaminants

Aqueous film forming foams (AFFFs) containing PFAS have been used since the 1960s for fire control and training for aviation crash and jet fuel spills at

Latest Publications

Feasibility of Metrological Traceability Implementation Using the Joint Committee on Traceability in Laboratory Medicine Database Entries Including the Fulfillment of "Fit-for-Purpose" Maximum Allowable Measurement Uncertainty

Author(s)
MAURO PANTEGHINI, Johanna Camara, VINCENT DELATOUR, Katleen Van Uytfanghe, Hubert Vesper, Tianjiao Zhang
Background: In previous publications, the Task Force on Reference Measurement System Implementation proposed a procedural approach combining a critical review

Software

chromatography program

Simulated Chromatographic Data

The following information is provided as an aid in the validation of mathematical models used in quantitation with chromatographic data. This data may also be
ABACUS Fiigure

The NIST ABACUS

Providing automated, virtual assistance in statistics for chemical analysis The NIST ABACUS ( App for Bayesian Analysis of Chemical quantities Using Shiny) is

Awards

Group Strat Award

Christina Jones, Benjamin Place and Aaron Urbas, together with CSD colleagues Regina Easley, Jason Waters, Laura Wood, Lee Yu, David Sheen and Werickson Rocha, received the 2019 MML Strategic Partnership Award for the establishment of a multidisciplinary team to conduct metrology research at NIST as part of the European Erasmus Mundus Joint Master in Quality in Analytical Laboratories (EMQAL) program.
PS1 group

Michael Nelson and Katrice Lippa, together with NIST colleagues Brian Lang, Jason Waters and Blaza Toman, received the Cooperation on International Traceability in Analytical Chemistry (CITAC) Best Paper Award for 2018 for their work on “A New Realization of SI for Organic Chemical Measurement: NIST PS1 Primary Standard for Quantitative NMR (Benzoic Acid)”.

Press Coverage

Featured Videos

NIST Chemist Melissa Phillips on Carbon

NIST Chemist Melissa Phillips on Carbon

NIST Analytical Chemistry Supports Industry and Health

NIST Analytical Chemistry Supports Industry and Health

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Blogs

Contacts

Group Leader

Office Manager