Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Search Patents by John P. Marino

Patents listed here reflect only technologies patented from FY 2018-present. To view all of NIST's patented technologies, visit the NIST pages on the Federal Laboratory Consortium website.

Displaying 1 - 2 of 2

Amino Acid-Specific Binder And Selectively Identifying An Amino Acid

NIST Inventors

John P. Marino and Zvi Kelman

N-terminal amino acid binding (NAAB) reagents are a tool for parallel, high-throughput proteomics. Afluorescently-labeled NAAB allows immobilized peptides to be identified by their N-terminal residues using single-molecule fluorescent microscopy, which enables novel proteomic analysis, like

Amino Acid-specific Binder and Selectively Identifying an Amino Acid

NIST Inventors

Zvi Kelman and John P. Marino

One of the central challenges in the development of single-molecule protein sequencing technologies is achieving high- fidelity, sequential recognition and detection of specific amino acids that comprise the peptide sequence. The N-End Rule Pathway adaptor protein ClpS, natively recognizes N