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Search Patents by Jacob Majikes

Patents listed here reflect only technologies patented from FY 2018-present. To view all of NIST's patented technologies, visit the NIST pages on the Federal Laboratory Consortium website.

Displaying 1 - 3 of 3

Nucleic Acid Nanostructures

NIST Inventors
Jacob Majikes and Veronika Szalai
Embodiments of the present invention relate to methods and composition of a nucleic acid tile with addressable locations for placement of molecular species that can function as sensors, reporters, or enhancers of measurement systems. Embodiments of the present invention may also include a nucleic

Agile Nucleic Acid Sensor And Measuring A Biomarker

NIST Inventors
Kevin Kiesler , Alokik Kanwal , Anthony J. Kearsley , Erica Romsos , Dr. Peter M. Vallone , Jacob Majikes and Arvind Balijepalli
An agile nucleic acid sensor includes: a DNA switch; an analysis substrate in electrostatic communication with the DNA switch and that produces a biomarker electrical signal; a transduction member that receives the biomarker electrical signal and produces a transduction signal; a sensor counter

DNA Nanotechnology-Based Biomarker Measurement Platform

NIST Inventors
Arvind Balijepalli and Jacob Majikes
We developed a new approach that utilizes the precise addressability of DNA nanotechnology constructs to allow quantitative biomolecule sensing with high sensitivity, specificity and reproducibility. Novel approaches to engineering DNA nanostructures allow the realization of tunable gain elements