Per- and Polyfluoroalkyl Substances – Non-Targeted Analysis Interlaboratory Study Final Report

Published

October 15, 2024

Author(s)

Benjamin Place, Jessica Reiner, Jared Ragland, Alix Rodowa, Carolyn Burdette, Amy Cuthbertson, Catherine Rimmer, John Kucklick, Nathan Mahynski

Abstract

Non-targeted analysis (NTA) is a technique for the identification of unknown chemicals in complex materials, such as novel per- and polyfluoroalkyl substances (PFAS) in environmental materials and commercial formulations. The PFAS NTA Interlaboratory Study (PFAS-NTAILS) was designed and administered to understand the measurement comparability of laboratories using NTA techniques for the identification of PFAS. Participating laboratories analyzed three samples containing varying amounts of PFAS and other chemicals and reported the identified PFAS in each of the samples. This report discusses the design of the PFAS-NTAILS study, the description of the participants and their methods, and the initial results of the study.

Citation

NIST Interagency/Internal Report (NISTIR) - 8544

Report Number

8544

NIST Pub Series

NIST Interagency/Internal Report (NISTIR)

Pub Type

NIST Pubs

Download Paper

https://doi.org/10.6028/NIST.IR.8544

Local Download

Keywords

Analytical chemistry, interlaboratory study, non-targeted analysis, mass spectrometry, per- and polyfluoroalkyl substances (PFAS)

Citation

Place, B. , Reiner, J. , Ragland, J. , Rodowa, A. , Burdette, C. , Cuthbertson, A. , Rimmer, C. , Kucklick, J. and Mahynski, N. (2024), Per- and Polyfluoroalkyl Substances – Non-Targeted Analysis Interlaboratory Study Final Report, NIST Interagency/Internal Report (NISTIR), National Institute of Standards and Technology, Gaithersburg, MD, [online], https://doi.org/10.6028/NIST.IR.8544, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=958688 (Accessed October 19, 2024)