Determination of Perfluorinated Alkyl Acid Concentrations in Biological Standard Reference Materials

Published

April 4, 2012

Author(s)

Jessica L. Reiner, Jennifer M. Lynch, Michele M. Schantz, Steven O'Connell, Craig M. Butt, Scott Mabury, Jeff Small, Amila De Silva, Derek Muir, Amy D. Delinsky, Mark J. Strynar, Andrew B. Lindstrom, William K. Reagen, Michelle Malinsky, Sandra Schafer, Christiaan Kwadijk

Abstract

Standard Reference Materials (SRMs) are homogeneous, well-characterized materials that are used to validate measurements and improve the quality of analytical data. The National Institute of Standards and Technology (NIST) has a wide range of SRMs that have values assigned for legacy organic pollutants. These SRMs can serve as target materials for method development and measurement for contaminants of emerging concern. Since inter-laboratory comparison studies have shown considerable disagreements when measuring perfluoroalkyl acids (PFAAs), future analytical measurements will benefit from the characterization of PFAAs in SRMs. NIST, in collaboration with multiple groups, has been measuring concentrations of PFAAs in a variety of SRMs. Here we report on levels of PFAAs and perfluorooctane sulfonamide (PFOSA) determined by the inter-laboratory participants in four SRMs: fish tissue (two materials), bovine liver, and mussel tissue. We also report concentrations for three in-house quality control materials: beluga whale liver, pygmy sperm whale liver, and white-sided dolphin liver. Measurements in SRMs show an array of PFAAs, with perfluorooctane sulfonate (PFOS) being the most frequently detected. Reference and information values are reported for PFAAs measured in these biological SRMs.

Citation

Analytical and Bioanalytical Chemistry

Volume

404

Pub Type

Journals

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DOI Link

Keywords

Perfluoroalkyl acids, Standard Reference Materials, Fish tissue, Bovine liver, Mussel tissue, Intercomparison exercise

Citation

Reiner, J. , Lynch, J. , Schantz, M. , O'Connell, S. , Butt, C. , Mabury, S. , Small, J. , De, A. , Muir, D. , Delinsky, A. , Strynar, M. , Lindstrom, A. , Reagen, W. , Malinsky, M. , Schafer, S. and Kwadijk, C. (2012), Determination of Perfluorinated Alkyl Acid Concentrations in Biological Standard Reference Materials, Analytical and Bioanalytical Chemistry, [online], https://doi.org/10.1007/s00216-012-5943-5 (Accessed November 21, 2024)