Potma, E.
, Jones, D.
, Cheng, J.
, Xie, X.
and Ye, J.
(2002),
High-Sensitivity Coherent Anti-Stokes Raman Scattering Microscopy With Two Tightly Synchronized Picosecond Lasers, Optics Letters
(Accessed January 2, 2025)
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High-Sensitivity Coherent Anti-Stokes Raman Scattering Microscopy With Two Tightly Synchronized Picosecond Lasers
Published
Author(s)
E Potma, D J. Jones, J X. Cheng, X. Xie,
Abstract
We demonstrate a significant improvement in signal-to-noise ratio in coherent anti stokes Raman Scattering (CARS) spectroscopy/microscopy, using two highly synchronized picosecond Ti: sapphire lasers. A temporal jitter between the pulse trains from the two independent commercial lasers is reduced from a few picoseconds to difference of} 21 fs, maintained over several hours. The tight synchronization brings the fluctuation of the CARS signal down to the shot-noise limit, leading to enhanced cARS vibrational images of living cells and polymer beads.Citation
Optics Letters
Volume
27
Issue
No. 13
Pub Type
Journals
Keywords
biological imaging, coherent anti-Stokes Raman scattering (C
Citation
Issues
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Created June 30, 2002, Updated October 12, 2021