Dizdar, M.
, Halliwell, B.
, Adhikary, A.
and Dingfelder, M.
(2021),
Hydroxyl radical is a significant player in oxidative DNA damage in vivo., Chemical Society Reviews, [online], https://doi.org/10.1039/D1CS00044F, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931588
(Accessed November 21, 2024)
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Hydroxyl radical is a significant player in oxidative DNA damage in vivo.
Published
Author(s)
, Barry Halliwell, Amitav Adhikary, Michael Dingfelder
Abstract
Recent publications have suggested that oxidative DNA damage mediated by hydroxyl radical (.OH) is unimportant in vivo, and that carbonate anion radical (CO3.-) plays the key role. We examine these claims and summarize the evidence that OH does play a key role as an important member of the reactive oxygen species (ROS) in vivo.Citation
Chemical Society Reviews
Pub Type
Journals
Download Paper
Keywords
hydroxyl radical, DNA damage, oxidative stress
Citation
Issues
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Created June 15, 2021, Updated October 14, 2021