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Displaying 251 - 275 of 482

Effective Strategies for Forensic Analysis in the Mitochondrial DNA Coding Region

January 1, 2006
Author(s)
Michael D. Coble, Peter Vallone, Rebecca S. Just, Toni M. Diegoli, Brion C. Smith, T. J. Parsons
Recently, it has been recognized that accessing information in the mitochondrial DNA (mtDNA) coding region can provide additional forensic discrimination with respect to the standard typing of the D-loop region, augmenting the sometimes rather limited

Repair of Formamidopyrimidines in DNA Involves Different Glycosylases - Role of the OGG1, NTH1, and NEIL1 Enzymes

December 9, 2005
Author(s)
J Hu, N de Souza-Pinto, K Haraguchi, Barbara A. Hogue, Pawel Jaruga, M M. Greenberg, Miral M. Dizdar, V. Bohr
2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) and 4,6-diamino-5-formamidopyrimidine (FapyA), are formed abundantly in DNA of cultured cells or tissues exposed to ionizing radiation or to other free radical-generating systems. We show here that FapyG

DNA Identifications After the 9/11 World Trade Center Attack

November 18, 2005
Author(s)
Leslie G. Biesecker, Joan E. Bailey-Wilson, Jack Ballantyne, Howard R. Baum, Frederick R. Bieber, Charles Brenner, Bruce Budowle, John M. Butler, George Carmody, P. M. Conneally, Barry Duceman, Arthur Eisenberg, Lisa Forman, Kenneth K. Kidd, Beno? Leclair, Steven Niezgoda, Thomas J. Parsons, Elizabeth Pugh, Robert Shaler, Stephen T. Sherry, Amanda Sozer, Anne Walsh

Standards and Standardization of Molecular Diagnostics

August 15, 2005
Author(s)
J P. Jakupciak, C D. O'Connell
DNA has become a major target for clinical laboratory testing over the past 5 years, and RNA testing is emerging for infectious disease and gene expression (1). To normalize laboratory results across different technology platforms as well as between

Mitochondrial DNA as a cancer biomarker

May 1, 2005
Author(s)
J P. Jakupciak, W. Wang, Maura E. Markowitz, D Ally, Michael D. Coble, Sudhir Srivastava, A Maitra, Peter E. Barker, David Sidransky, Catherine D. O'Connell

Standards for Validation of Cancer Biomarkers

April 2, 2005
Author(s)
Catherine D. O'Connell, Donald H. Atha, J P. Jakupciak
Over the past 10 years, DNA testing to identify disease associated mutations and specific organisms, which represent public health and safety concerns, have become major targets for laboratory testing. RNA testing is also emerging for gene expression, both
Displaying 251 - 275 of 482