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Search Publications by: Dr. Vincent A. Hackley (Assoc)

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Displaying 151 - 175 of 305

Tumor Necrosis Factor Interaction with Gold Nanoparticles

March 14, 2012
Author(s)
De-Hao D. Tsai, Sherrie R. Elzey, Frank W. DelRio, Robert I. MacCuspie, Suvajyoti S. Guha, Michael R. Zachariah, Athena M. Keene, Jeffrey D. Clogston, Vincent A. Hackley
We report on a systematic investigation of molecular conjugation of tumor necrosis factor protein-α (TNF) onto gold nanoparticles (AuNPs) and the subsequent binding behavior to its antibody (anti-TNF). We employ a combination of physical and spectroscopic

Quantification of ligand packing density on gold nanoparticles using ICP-OES

February 18, 2012
Author(s)
Sherrie R. Elzey, De-Hao D. Tsai, Savelas A. Rabb, Lee L. Yu, Michael R. Winchester, Vincent A. Hackley
In this study, a prototypical thiolated organic ligand, 3-mercaptopropionic acid (MPA), was conjugated on gold nanoparticles (AuNPs), and packing density was measured on an ensemble-averaged basis using inductively coupled plasma optical emission

Size Measurement of Nanoparticles Using Atomic Force Microscopy, ASTM E2859-11

January 2, 2012
Author(s)
Jaroslaw Grobelny, Frank W. DelRio, Pradeep Namboodiri, Doo-In Kim, Vincent A. Hackley, Robert F. Cook
The purpose of this document is to provide guidance on the quantitative application of atomic force microscopy (AFM) to determine the size of nanoparticles2 deposited in dry form on flat substrates using height (z-displacement) measurement. Unlike electron

Quantitative Determination of Competitive Molecular Adsorption on Gold Nanoparticles Using Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy

June 28, 2011
Author(s)
De-Hao D. Tsai, Melissa Davila-Morris, Frank W. DelRio, Suvajyoti S. Guha, Vincent A. Hackley, Michael R. Zachariah
Surface-sensitive quantitative studies of competitive molecular adsorption on nanoparticles were conducted using a modified Attenuated attenuated Total total Reflectionreflectance-Fourier Transform transform Infrared infrared (ATR-FTIR) spectroscopy method

Hydrodynamic Fractionation of Finite Size Nano Gold Clusters

June 15, 2011
Author(s)
De-Hao D. Tsai, Tae Joon Cho, Frank W. DelRio, Julian S. Taurozzi, Michael R. Zachariah, Vincent A. Hackley
We demonstrate a high resolution in situ experimental method for performing simultaneous size-classification and characterization of functional nanoscale gold clusters (NGCs) based on asymmetric-flow field flow fractionation (AFFF). Field emission scanning

Interlaboratory Reproducibility of Size and Surface Charge Measurements on Nanoparticles prior to Biological Impact Assessment

June 3, 2011
Author(s)
Gert Roebben, Sonia Ramirez-Garcia, Vincent A. Hackley, Matthias Roesslein, Fred Klaessig, Vikram Kestens, Iseult Lynch, C. M. Garner, Alan Rawle, Allison Elder, Vicky Colvin, Wolfgang Kreyling, Harald Krug, Zuzanna Lewicka, Scott McNeil, Andre Nel, Anil K. Patri, Peter Wick, Tian Xia, Guenther Oberdoerster, Kenneth Dawson
The International Alliance for NanoEHS Harmonization (IANH) organises interlaboratory comparisons of methods relevant for a better understanding of the biological impacts of nano-objects, to highlight and remove sources of irreproducibility in existing