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Search Publications by: Paul Butler (Fed)

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Displaying 1 - 25 of 79

Anisotropy Factors in Small-Angle Scattering for Dilute Rigid-Rod Suspensions

June 1, 2023
Author(s)
Jack Rooks, Peter H. Gilbert, Lionel Porcar, Yun Liu, Paul Butler
Alignment of anisotropic particles along specific orientations influences the mechanical and rheological properties of a material. Small-angle scattering techniques are widely used to probe this alignment through analysis of anisotropic two-dimensional sca

Relationship between Viscosity and Acyl Tail Dynamics in Lipid Bilayers

August 12, 2021
Author(s)
Michihiro Nagao, Elizabeth Kelley, Antonio Faraone, Makina Saito, Yoshitaka Yoda, Masayuki Kurokuzu, Shinichi Takata, Makoto Seto, Paul Butler
Membrane viscosity is a fundamental property that controls molecular transport and structural rearrangements in lipid membranes. Given its importance in many cell processes, various experimental and computational methods have been developed to measure the

Collective Dynamics in Lipid Membranes Containing Transmembrane Peptides

June 21, 2021
Author(s)
Elizabeth Kelley, Paul Butler, Michihiro Nagao
Biological membranes are composed of complex mixtures of lipids and proteins that influence each other's structure and function. The biological activities of many channel-forming peptides and proteins are known to depend on the material properties of the

Enhance Dynamics in the Anomalous Melting Regime of DMPG Lipid Membranes

October 16, 2020
Author(s)
Elizabeth Kelley, Michihiro Nagao, Paul Butler, Lionel Porcar, Bela Farago
Like many soft materials, lipids undergo a melting transition associated with a significant increase in their dynamics. At temperatures below the main melting transition (T m), all molecular and collective dynamics are suppressed, while above T m the alkyl

Scaling Relationships for the Elastic Moduli and Viscosity of Mixed Lipid Membranes

September 21, 2020
Author(s)
Elizabeth Kelley, Paul Butler, Rana Ashkar, Robert Bradbury, Michihiro Nagao
The elastic and viscous properties of biological membranes play a vital role in controlling cell functions that require local reorganization of the membrane components as well as dramatic shape changes such as endocytosis, vesicular trafficking, and cell

In Situ Neutron Scattering of Antibody Adsorption during Protein A Chromatography

April 26, 2020
Author(s)
Maria Papachristodoulou, James Doutch, Hoi Sang Beatrice Leung, Andy Church, Thomas Charleston, Luke A. Clifton, Paul Butler, Christopher J. Roberts, Daniel G. Bracewell
A deeper understanding of the nano and mesoscale structure of chromatographic adsorbents and the distribution of proteins within the media, is critical to a mechanistic understanding of separation processes using these materials. Characterisation of the

Scaling of Lipid Membrane Rigidity with Domain Area Fraction

February 21, 2019
Author(s)
Elizabeth G. Kelley, Michihiro Nagao, Paul D. Butler
The elastic properties of cell membranes play a vital role in controlling the morphology changes necessary for cell processes such as endocytosis and cell division. These elastic properties are highly sensitive to the lipid composition and distribution

Quantification of Carbon Nanotube Liquid Crystal Morphology via Neutron Scattering

September 11, 2018
Author(s)
Francesca Mirri, Rana N. Ashkar, Vida Jamali, Lucy Liberman, Robert A. Pinnick, Paul van der Schoot, Yeshayahu Talmon, Paul Butler, Matteo Pasquali
Liquid phase assembly is among the most industrially attractive routes for scalable carbon nanotube (CNT) processing. Chlorosulfonic acid (CSA) was found to be an ideal solvent for CNTs, spontaneously dissolving them without compromising their properties

Small-Angle X-ray and Neutron Scattering Demonstrates that Cell-Free Expression Produces Properly Formed Disc-Shaped Nanolipoprotein Particles

December 20, 2017
Author(s)
Thomas E Cleveland, Wei He, Angela C. Evans, Nicholas O. Fischer, Matthew A. Coleman, Paul Butler
Nanolipoprotein particles (NLPs), composed of a membrane scaffold protein and lipids, have been used to support membrane proteins in a native-like bilayer environment for biochemical or structural studies. Traditionally, these NLPs have been prepared by