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Search Publications by: Nancy Lin (Fed)

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Displaying 26 - 50 of 83

Experimental and statistical methods to evaluate antibacterial activity of a quaternary pyridinium salt on planktonic, biofilm-forming, and biofilm states

March 3, 2017
Author(s)
Daneli Lopez-Perez, Paula J. Baker, Adam L. Pintar, Jirun Sun, Nancy Lin, Sheng Lin-Gibson
Robust evaluation and comparison of antimicrobial technologies are critical to improving biofilm prevention and treatment. Herein, a multi-pronged experimental framework and statistical models were applied to determine the effects of quaternary pyridinium

Automation of Antimicrobial Activity Screening

March 12, 2016
Author(s)
Samuel P. Forry, Meggan C. Madonna, Daneli Lopez-Perez, Nancy J. Lin, Madeleine D. Pasco
ABSTRACT: Manual and automated methods were compared for routine screening of compounds for antimicrobial activity. Automation generally accelerated assays and required less user intervention while producing comparable results. Automated protocols were

Solution-based functionalization of gallium nitride nanowires for protein sensor development

April 17, 2014
Author(s)
Albert Davydov, Elissa H. Williams, Vladimir P. Oleshko, Kristen L. Steffens, Igor Levin, Nancy J. Lin, Kristine A. Bertness, Amy Manocchi, M V. Rao, John A. Schreifels
A solution-based functionalization method for the specific and selective attachment of the streptavidin (SA) protein to gallium nitride (GaN) nanowires (NWs) is presented. By exploiting streptavidin's strong affinity for its ligand biotin, SA

Effects of dual antibacterial agents MDPB and nano-silver in primer on microcosm biofilm, cytotoxicity and dentin bond properties

February 1, 2013
Author(s)
Ke Zhang, Lei Cheng, Satoshi Imazato, Joseph M. Antonucci, Nancy Lin, Sheng Lin-Gibson, Yuxing Bai, Hockin H. Xu
Objectives: Secondary caries at restoration margins is the main reason for restoration failure. Antibacterial bonding agents are promising to inhibit biofilm acids at the tooth-restoration interfaces. The objective of this study was to investigate the

Selective Streptavidin Bioconjugation on Si and SiC nanowires for Biosensor Applications.

January 14, 2013
Author(s)
Elissa H. Williams, John A. Schreifels, Mulpuri V. Rao, Albert Davydov, Vladimir P. Oleshko, Nancy J. Lin, Kristen L. Steffens, Sergiy Krylyuk, Kristine A. Bertness, Amy Manocchi, Yaroslav Koshka
A functionalization method for the specific and selective immobilization of the streptavidin (SA) protein on semiconductor nanowires (NWs) was developed. Silicon (Si) and silicon carbide (SiC) NWs were functionalized with 3-aminopropyltriethoxysilane

Selective Streptavidin Bioconjugation on Si, SiC, and GaN Nanowires for Biosensor Applications.

October 19, 2012
Author(s)
Elissa H. Williams, John A. Schreifels, Mulpuri V. Rao, Albert Davydov, Vladimir Oleshko, Nancy Lin, Kristen L. Steffens, Sergiy Krylyuk, Kristine A. Bertness, Amy Manocchi, Yaroslav Koshka
A functionalization method for the specific and selective immobilization of the streptavidin (SA) protein on semiconductor nanowires (NWs) was developed. Silicon (Si), silicon carbide (SiC), and gallium nitride (GaN) NWs were functionalized with 3

Effect of Polymer Degree of Conversion on Streptococcus mutans Biofilms

October 5, 2012
Author(s)
Alison M. Kraigsley, Kathy Tang, John A. Howarter, Katrice Lippa, Sheng Lin-Gibson, Nancy Lin
The effects of key material properties of polymeric composite restorations on cariogenic oral biofilms are needed to provide insight into the materials' role in recurrent caries. The objective of this study was to quantify the effects of degree of

Antibacterial nanocomposites containing amorphous calcium phosphate and silver nanoparticles with different filler levels

May 7, 2012
Author(s)
Lei Cheng, Michael D. Weir, Hockin H. Xu, Joseph M. Antonucci, Nancy Lin, Sheng Lin-Gibson, Sarah M. Xu, Xuedong Zhou
A dental composite containing amorphous calcium phosphate nanoparticles (NACP) was developed that released high levels of calcium (Ca) and phosphate (PO4) ions and possessed acid neutralization capability. There has been little study on incorporation of

Positively-charged Dimethacrylates to Reduce Bacterial Attachment

March 30, 2012
Author(s)
Nancy J. Lin, Joseph M. Antonucci, Diana N. Zeiger, Sheng Lin-Gibson, Kathy Tang
The widespread incidence of recurrent tooth decay (caries) highlights the need for improved dental restorative materials. Caries are most frequently caused by acid-producing bacterial biofilms. One approach for developing biomaterials with reduced

Antibacterial amorphous calcium phosphate nanocomposite with quaternary ammonium salt and silver nanoparticles

February 2, 2012
Author(s)
Nancy Lin, Lei Cheng, Michael D. Weir, Hockin H. Xu, Joseph M. Antonucci, Alison M. Kraigsley, Sheng Lin-Gibson, Xuedong Zhou
Objectives. Calcium and phosphate ion-releasing resin composites are promising for remineralization; however, so far there has been no report on imparting a potent antibacterial capability to these composites. The objectives of this study were to