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Search Publications by: Illarion Turko (Fed)

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Displaying 76 - 86 of 86

Optimizing the Conditions of a Multiple Reaction Monitoring Assay for Membrane Proteins: Quantification of Cytochrome P450 11A1 and Adrenodoxin Reductase in Bovine Adrenal Cortex and Retina

July 1, 2010
Author(s)
Illarion V. Turko, Wei-Li Liao, Gun-Young Heo, Nathan G. Dodder, Irina A. Pikuleva
Although 30% of naturally occurring proteins are predicted to be embedded in biological membranes, membrane proteins are traditionally understudied due to limitations of the available analytical tools. To be applicable to the analysis of membrane proteins

Accumulation of Large Protein Fragments in Prematurely Senescent ARPE-19 Cells

October 1, 2009
Author(s)
Illarion V. Turko, Wei-Li Liao
Senescence of retinal pigment epithelial (RPE) cells is a crucial event in the pathogenesis of age-related macular degeneration (AMD). This study was design to improve the understanding of changes that underlie the RPE senescence. The levels of various

A new approach to assess mAb aggregation

January 1, 2001
Author(s)
Illarion Turko
A proof-of-concept for new methodology to detect and potentially quantify mAb aggregation is presented. Assay development included using an aggregated mAb as bait for screening of a phage display peptide library and identifying those peptides with random

Quantitative Proteomic Profiling of Prematurely Senescent ARPE-19 Cells

January 1, 2001
Author(s)
Illarion Turko, Wei-Li Liao
Senescence of retinal pigment epithelial (RPE) cells is a crucial event in the pathogenesis of age-related macular degeneration (AMD). ARPE-19 is a nontransformed human RPE cell line that displays many differentiated properties typical of RPE in vivo. The