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Search Publications by: Hua-Jun He (Fed)

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Displaying 26 - 46 of 46

Negative Regulation of STAT3-mediated Cellular Respiration by SirT1

June 7, 2011
Author(s)
Lili Wang, Hua-Jun He, Michel Bernier, Rajib K. Paul, Alejandro Martin-Montalvo, Morten Scheibye-Knudsen, Shaoming Song, Sean M. Armour, Vilhelm A. Bohr, Yaping Zong, David A. Sinclair, Rafael de Cabo
In mammals, the transcriptional activity of signal transducer and activator of transcription 3 (STAT3) is regulated by the deacetylase SirT1. However, whether the newly described non-genomic actions of STAT3 toward mitochondrial oxidative phosphorylation

Development of a Candidate Secondary Reference Procedure (immunoassay based measurement procedure of higher metrological order) for Cardiac Troponin I: I. Antibody Characterization and Preliminary Validation

November 1, 2010
Author(s)
James E. Noble, David M. Bunk, R. H. Christenson, Kenneth D. Cole, Hua-Jun He, Alexei Katrukha, Mauro Panteghini, Robert Porter, Heinz Schimmel, Jillian Tate, Lili Wang
The development of a reference measurement procedure to support the cardiac troponin I (cTnI) standardization initiative is described. The reference measurement procedure will be used to assign reference values to serum-based secondary standards. A

Sensing the Insulin Signaling Pathway with an Antibody Array

December 1, 2009
Author(s)
Hua-Jun He, Y Zong, Michel Bernier, Lili Wang
Defects within the insulin signaling pathways are a major locus for the development of insulin resistance and type 2 diabetes. The phorbol 12-myristate 13-acetate (PMA) is commonly described as a mediator of insulin resistance through the activation of the

Epitope Selection of Monoclonal Antibodies for Interleukin-4 Quantification Using Suspension Arrays and Forward-Phase Protein Microarrays

December 6, 2007
Author(s)
Lili Wang, Kenneth D. Cole, Hua-Jun He, Alexander W. Peterson, Adolfas K. Gaigalas, Y Zong
A recombinant mouse interleukin-4 (IL-4) and three different purified rat anti-mouse IL-4 monoclonal antibodies (Mab) with different epitopes were employed as a model system. This system was used to examine monoclonal antibody effectiveness using both