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Search Publications by: Sumona Sarkar (Fed)

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Displaying 26 - 33 of 33

Machine Learning Analysis for Identification of Cell Shape Metrics Associated with Stem Cell Differentiation in Nanofiber Scaffolds

April 19, 2014
Author(s)
Desu Chen, Sumona Sarkar, Stephen J. Florczyk, Subhadip Bodhak, Carl G. Simon Jr., Joy P. Dunkers, Julian Candia, Wolfgang Losert
Cell shape has been demonstrated to be closely related to cell function and may be an important predictor of cell fate. Many metrics are available to describe cell shape, however the relationship of these metrics to cell fate are not well understood

Airbrushed Nanofiber Scaffolds Support Bone Marrow Stromal Cell Differentiation

November 1, 2013
Author(s)
Carl G. Simon Jr., Wojtek J. Tutak, Sumona Sarkar, Tanya M. Farooque, Jyotsnendu J. Giri, Dongbo Wang, Sheng Lin-Gibson, Joachim Kohn, Durgadas Bolikal
Nanofiber scaffolds are effective for tissue engineering since they emulate the fibrous nanostructure of native extracellular matrix (ECM). Although electrospinning has been the most common approach for fabricating nanofiber scaffolds, airbrushing

Effect of Surface Chemistry on Stem Cell Response in 2-D vs. 3-D Cell Culture Niches

April 19, 2013
Author(s)
Sumona Sarkar, Carl G. Simon Jr., Roberta I. Lock, Joy P. Dunkers
To develop tissue engineered devices for regenerative medicine strategies, key scaffold properties for directing stem cell response must be identified. As focus shifts from 2-D to 3-D culture systems in an attempt to better recapitulate the natural