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Search Publications by: Svetlana Ikonomova (Fed)

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Using enantioselective biosensors to evolve asymmetric biocatalysts

January 30, 2025
Author(s)
d'Oelsnitz Simon, Wantae Kim, Haley Hardtke, Svetlana Ikonomova, Nina Alperovich, Olga Vasilyeva, Michael James, Eric Zigon, Charlie Johnson, Andrew Ellington, Quincey Justman, Michael Springer, Jessie Zhang, Pamela Silver, David Ross
Biocatalysts are championed for their exquisite stereochemistry, but slow chromatographic separations necessary to measure enantiomeric excess can bottleneck their development. Prokaryotic transcription factors can address this limitation by transducing