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Search Publications by: Geoffrey Taghon ()

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Displaying 1 - 2 of 2

High-throughput DNA engineering by mating bacteria

September 3, 2024
Author(s)
Takeshi Matsui, Po-Hsiang Hung, Han Mei, Xianan Liu, Fangfei Li, John Collins, Weiyi Li, Darach Miller, Neil Wilson, Esteban Toro, Geoffrey Taghon, Gavin Sherlock, Sasha Levy
To reduce the operational friction and scale DNA engineering, we report here an in vivo DNA assembly technology platform called SCRIVENER (Sequential Conjugation and Recombination for In Vivo Elongation of Nucleotides with low ERrors). SCRIVENER combines

Advances in Yeast Synthetic Biology for Human GPCR Biology and Pharmacology

July 29, 2024
Author(s)
Geoffrey Taghon, Nicholas Kapolka, Daniel Isom
G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors in humans. Over 800 GPCRs regulate the (patho)biology of every organ, tissue, and cell type. Consequently, GPCRs are the most prominent therapeutic targets in medicine