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UV Stabilizer BTMPS in the Illicit Fentanyl Supply in 9 US Locations

Published

Author(s)

Chelsea Shover, Morgan Godvin, Meghan Appley, Elise Pyfrom, Fernando Montero Castrillo, Karli Hochstatter, Neil Garg, Adam Koncsol, Joseph Friedman, Caitlin Molina, Ruby Romero, Brendan Harshberger, Jordan Spoliansky, Candace Winstead, Edward Sisco

Abstract

Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (BTMPS) belongs to a class of molecules called hindered amine light stabilizers that are used in plastics manufacturing and as adhesives or sealants.1 BTMPS has not been studied in humans or approved for human consumption, but animal studies have revealed cardiotoxicity, ocular damage, sudden death, other adverse health effects, and nicotinic antagonist effects.2,3 In this study, we characterize BTMPS's introduction to the illicit fentanyl supply in 9 US locations.
Citation
Jama-Journal of the American Medical Association

Keywords

Opioids, Fentanyl, Drug Checking, Public Health

Citation

Shover, C. , Godvin, M. , Appley, M. , Pyfrom, E. , Montero Castrillo, F. , Hochstatter, K. , Garg, N. , Koncsol, A. , Friedman, J. , Molina, C. , Romero, R. , Harshberger, B. , Spoliansky, J. , Winstead, C. and Sisco, E. (2025), UV Stabilizer BTMPS in the Illicit Fentanyl Supply in 9 US Locations, Jama-Journal of the American Medical Association, [online], https://doi.org/10.1001/jama.2024.27550, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=958683 (Accessed April 3, 2025)

Issues

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Created February 5, 2025, Updated February 8, 2025