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Bioscience & Health Portal -- Overview

New medical diagnostic tests, improving the quality and cost-effectiveness of health care electronic records, reference materials for laboratory test methods, faster screening of promising vaccines, these are a few of the many areas where National Institute of Standards and Technology (NIST) research serves the needs of the bioscience and health care community. NIST collaborates extensively with other federal and private organizations to provide the new measurements and standards methods, tools, and data needed to advance biosciences and health research. Bioscience and Health represent a large portion of that content.

Institute for Bioscience and Biotechnology Research>>
Hollings Marine Laboratory>>

Programs and Projects
Whole Cell Tomography

Our goal is to develop novel correlative microscopy approaches for locating and characterizing engineered metal nanoparticles within complex … more

Fundamental Chemical Metrology

The Chemical Sciences Division serves as the Nation’s reference laboratory for chemical compositional measurements and standards to enhance U.S. … more

Marine Environmental Metabolomics

NIST is developing NMR-based metabolomics for use as a tool to expand research on the impacts of environmental stressors on marine organisms. The … more

Protein rheology measurements

Therapeutic protein solutions are highly concentrated during manufacturing purification processes and in finished dosage. At such concentrations, … more

HDX-MS for Biopharmaceutical Analysis

This project applies hydrogen/deuterium exchange mass spectrometry (HDX-MS) for determining the dynamical structure of therapeutic antibodies, … more

Development of Standard Reference Materials for Vitamin D Metabolites

The prevalence of vitamin D deficiency/insufficiency within the general population is an area of concern. Vitamin D status is generally assessed by … more

Software
NIST Mass and Fragment Calculator Software

The NIST Mass and Fragment Calculator is a program written in Visual Basic which calculates the mass of an input peptide or protein sequence along … more

NIST's Integrated colony enumerator (NICE)

Enumeration of bacterial colonies on an agar plate is simple in concept, but automated colony counting is difficult due to variations in colony … more

Isotope Enrichment Calculator

The NIST Isotope Enrichment Calculator is a program written in Visual Basic which determines the percentage of 15 N enrichment of stable … more

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