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Bioscience & Health Programs & Projects

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Multiparametric Measurement and Analysis of Cell Behavior on Extracellular Matrices
Last Updated Date: 10/10/2012

Cell responses to their culture environment always involve more than one component. An understanding of the relation between the physical and … more

26plex Autosomal Short Tandem Repeat Assay
Last Updated Date: 10/08/2012

A short tandem repeat (STR) multiplex assay was developed with 25 autosomal loci plus the sex-typing locus amelogenin for a total of 26 amplified … more

DNA Mixture Interpretation
Last Updated Date: 10/08/2012

Based on data collected over the last year from various forensic labs, (see http://www.cstl.nist.gov/biotech/strbase/mixture.htm ) the majority of … more

Rapid Multiplex PCR
Last Updated Date: 10/08/2012

Forensic DNA typing is currently conducted in approximately eight to ten hours. The process includes DNA extraction, quantitation, multiplex PCR … more

Rapid Measurement of Aggregation of Protein Therapeutics During Biomanufacturing
Last Updated Date: 10/05/2012

Protein therapeutics is the largest class of drugs made by the biotechnology industry. Aggregation of protein therapeutics is a major safety … more

Site-Specific Bioimaging
Last Updated Date: 10/02/2012

In collaboration with scientists at the Laboratory for Cell Biology (LCB) within the National Cancer Institute (NCI) of the National Institutes of … more

Next-Generation Metrology for Drug Delivery Systems
Last Updated Date: 10/02/2012

A critical metrology issue for pharmaceutical industries is the application of analytical techniques to the characterization of drug delivery … more

Trophic Transfer of Nanoparticles in a Simplified Invertebrate Food Web
Last Updated Date: 10/02/2012

We demonstrated that carboxylated and biotinylated quantum dots (QDs) can be transferred to higher trophic organisms (rotifers) through dietary … more

Depth Profiling of Drug Eluting Stent Coatings with Cluster SIMS
Last Updated Date: 10/02/2012

There is much excitement in the cardiology community about drug eluting stents (DES), a promising new treatment for coronary artery disease. A … more

3D Molecular Bioimaging Mass Spectrometry
Last Updated Date: 10/02/2012

In recent years, the use of cluster primary ion projectiles for organic secondary ion mass spectrometry (SIMS) has generated considerable interest … more

Thermophysical Properties of Biofuels
Last Updated Date: 10/01/2012

The Thermophysical Properties Division has begun a program to develop thermophysical property data for the biofuels. Transportation fuels will … more

Biocompatibility of Photoluminescent Silicon Nanoparticles
Last Updated Date: 10/01/2012

Photoluminescent silicon nanoparticles have a bright and stable fluorescence and are promising candidates for use in bio-imaging, cell staining … more

Ontologies and Interoperability in Evolutionary Comparative Analysis
Last Updated Date: 10/01/2012

Many computer-based inferences in contemporary biology are comparative and would benefit from the rigorous and flexible approach of evolutionary … more

Structural Databases
Last Updated Date: 10/01/2012

We are witnessing the emergence of a web based "data rich" era on chemical and biological compounds. In order to make significant advances in this … more

Decontamination of Biological Threats in Water Supplies
Last Updated Date: 10/01/2012

The availability of safe pure drinking water in the United States is taken for granted. The presence of dangerous microorganisms, viruses and … more

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