Michael Boss, Katy Keenan, Stephen Russek and Karl Stupic are recognized for advancing the forefront of biomedical imaging by developing a broad suite of calibration “phantoms” to enable quantitative magnetic resonance imaging (MRI) for the unambiguous measurement of disease progression and treatment efficacy. Each phantom in the team’s toolbox is targeted to ensure quantitative MRI images for the different medical needs, including traumatic brain injury, cancer, neurodegenerative diseases, breast cancer, and general imaging. These standards are in use in multi-site clinical trials around the world. Through quick action, the NIST team has transferred phantom development to Colorado-based High Precision Devices, Inc. to enable more widespread adoption of the MRI phantom protocols.