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Material Measurement Laboratory

Projects/Programs

Displaying 101 - 125 of 566
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Cruciform Multiaxial Mechanical Testing

Ongoing
A new ARRA funded cruciform test machine is being installed in the NIST Center for Automotive Lightweighting. Its capabilities include 500kN load per axis, two DIC strain mapping systems (one for large field mapping and one for zooming in to study localizations or features), a high resolution, high

Crystal Plasticity Modeling of Yield Surface Evolution

Completed
A robust multiaxial constitutive law is needed to predict stresses within parts formed from sheet metal to be able to compensate for such phenomena as elastic springback. Ideally, the constitutive law would not need to be "trained" using empirical mechanical property data alone, but would be able to
blue crystal

Crystallographic Databases

Ongoing
Impact and Customers Materials with new or improved properties are continually being developed to meet demands for increased functionality of components and devices at decreased costs. Examples of multi-million dollar industries driven by materials advances are solid-state lighting (GaN-based

AI/ML for Data Extraction and Uncertainty Predictions

Ongoing
The Material Measurement Lab at NIST employs artificial intelligence for the prediction and discovery of materials characteristics. Our applications of artificial intelligence (AI) accelerate materials research as well as help the community learn about AI's capabilities and gain confidence in
Big data analysis report on 3D effects.AI technology generated image

Data Tools for Environmental Metrology

Ongoing
A recent addition to operations in the NIST Biorepository, we seek out places where NIST scientists get bogged down by the complexity of their data. Research at NIST can generated some of the most complex data in the world, at times requiring six months or more of processing to get to the data

Decontamination of Biological Threats in Water Supplies

Completed
The outcome of the project was to provide the EPA with a technical resource document that could be used to guide emergency responders and for longer-term microbial decontamination of building water systems. This project was done in collaboration with the Building and Fire Research Laboratory (BFRL)

Deducing Prior Material Deformation from Simple Mechanics

Ongoing
Process-structure-property linkages suggest an opportunity to deduce processing from behavior. Simple imaging experiments provide rich sources of data. Can we deduce prior deformation? Scheme: Thin film plasticity Deform to some reference strain Unload Deform to test strain, image Deduce

Determinations of Boron Deposit Quality by Neutron Depth Profiling

Ongoing
Neutrons are not easily detected with high resolution and good efficiency. Consequently, high-quality neutron detectors remain a challenge to manufacture. A few nuclides such as He-3, Boron-10, and Li-6 are commonly used to convert impinging neutrons into an electrical pulse that post-processing

Developing a Materials Innovation Infrastructure

Completed
Phase Field Community Hub ( PFHub) and Benchmarks The Phase Field Community Hub provides a framework that supports phase field practitioners and code developers participating in an effort to improve quality assurance for phase field codes. The main thrust of this effort is the generation of a set of

Development of Biomarker-based Systems for Cancer Detection and Therapy

Completed
Intended impact Although significant progress has been made in both the understanding and treatment of cancer during the last thirty years, it remains the second leading cause of death in the US. The cancer community has set a goal to eliminate cancer-related suffering and death by 2015. To achieve

Development of Enhanced mRNA Amplification Using Microfluidics

Completed
Intended Impact Tissue samples frequently contain multiple cell types. New methods (e.g. laser capture microdissection) enable the segregation of small quantities of individual cells and cell types, but the current methods to analyze global gene expression do not provide highly efficient profiling

Development of the NIST Prototype Advanced Biometrology Laboratory

Ongoing
Currently, NIST is investing in a new type of metrology laboratory that is focused on the unique reference material and high quality assay protocols that are needed in the regenerative medicine and biotechnology communities. The laboratory design is centered on automation that can set up 1000’s of

Development of Proteomics-Based Methods for Protein Quantification

Ongoing
Reference measurement procedures and standard reference materials help ensure that routine clinical assays provide accurate results across different laboratories and over time. Lists of such higher-order methods are published by the Joint Committee for Traceability in Laboratory Medicine (JCTLM)

Development of Reference Methods and Reference Materials for Proteins

Ongoing
Accuracy and comparability of clinical assays is essential for timely and accurate medical interventions. However, studies have shown that large variations in results can occur among routine clinical assays. A clinical comparison among 14 commercial assay platforms revealed more than 20-fold