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Projects/Programs

Displaying 1 - 10 of 10

Clinical and Forensic Reference Materials

Ongoing
Below is a listing of the reference materials currently produced by the Applied Genetics group. Clinical Diagnostics SRM 2393 - CAG Repeat Length Mutation in Huntington`s Disease SRM 2365 - BK Virus DNA Quantitative Standard SRM 2366a - Cytomegalovirus DNA (Towne Δ147 BAC) for DNA SRM 2367 - JC

Decontamination of Biological Threats in Water Supplies

Completed
The outcome of the project was to provide the EPA with a technical resource document that could be used to guide emergency responders and for longer-term microbial decontamination of building water systems. This project was done in collaboration with the Building and Fire Research Laboratory (BFRL)

Digital PCR

Ongoing
With appropriately validated assays, digital polymerase chain reaction (dPCR) determines the number of DNA targets (copies) per reaction partition, without the need for a standard curve. Reaction partitions can be in the form of fixed chambers in a microfluidic device, referred to as chamber digital

DNA Mixture Interpretation

Ongoing
Interlaboratory Studies Mixture interlaboratory studies provide a means to assess a laboratory's ability to process and interpret DNA mixtures. Initial ‘Mixed Stain’ studies (published in 2001) provided physical samples for DNA profiling with the first commercial STR typing tests. Later, mixture

DNA Technical Leader Survey

Ongoing
Please click here to start the survey The survey is now live and will close on June 17, 2022 (deadline has been extended). It is open to both U.S. and international agencies. It is to be completed by one person from each DNA laboratory – the Technical Leader (or equivalent). Frequently Asked

Expert Working Group on Human Factors in Forensic DNA Interpretation

Completed
Forensic DNA interpretation is widely regarded as a critical tool in modern criminal investigations, often seen as the gold standard of forensic evidence due to its potential to help link individuals to crime scenes. The process begins with the collection and preservation of DNA samples—from blood

Forensic Genetics

Ongoing
Since the late 1980s, NIST has had scientists involved in DNA testing (aka "DNA Fingerprinting"). Early concerns over measurement accuracy and poor quality control of forensic DNA tests caused the Department of Justice to call upon NIST scientists to help with standards development and technology

Micro- and Nanoelectromechanical Systems

Completed
MEMS/NEMS are enabling technologies that bring new functionalities with the potential to radically transform markets ranging from consumer products to national defense. The meteoric rise of the smartphone is an excellent example, in which MEMS accelerometers, gyroscopes, microphones, displays, and

Toxicology

Ongoing
Development of Low-Volume Drop Blood Drug Screening Tools This project aims to leverage recent NIST advances in ambient ionization mass spectrometry to develop platforms for low-volume blood drug screening. Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Paper Spray Ionization Mass