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Projects/Programs

Displaying 1 - 25 of 156

AAPS Interlaboratory Study: Protein Aggregation and Immunogenicity

Ongoing
To ensure the safety and efficacy of protein-based biotherapeutics, manufacturers strive to avoid unwanted immune responses caused by the biotherapeutic. Protein immunogenicity is a complex topic and depends on multiple factors related to the product, patient profile, and treatment. 1 , 2

Accelerated Weathering Laboratory: Metrology and Technology Transfer

Ongoing
Objective By 2027, validate and implement the NIST Accelerated Weathering Laboratory (AWL) technology for conducting accurate and traceable aging experiments. By 2028, transfer the SPHERE technology to industrial stakeholders. Technical Idea A NIST Accelerated Weathering Laboratory (AWL) has been

Additive Manufacturing Fatigue and Fracture

Ongoing
Metal additive manufacturing (AM) is not used in fatigue and fracture critical applications despite industrial need. The goal of this project is to enable confident use of metal AM in critical applications through: Advancing metrological practice for AM-specific performance metrics encompassing the

Advanced Cements and Concretes Consortium

Ongoing
For more information visit the NIST Carbon Capture and Carbon Sequestration project page. consortium goals The initial focus of this consortium is to evaluate, develop, and standardize methods to characterize and quantify the carbon and carbonates in new cements and concretes. Test methods to

Advanced Composites Pilot for the Materials Genome Initiative

Completed
Many computational programs exist that are being used by industry for predicting properties of polymer composites but their general predictive power is limited by how faithfully the microstructure is represented and how realistically the interfaces are handled. The computations are limited by the

Advanced Materials Metrology

Ongoing
Electromagnetic devices cannot operate without the interaction of electromagnetic waves with materials, and the characterization of the interface between fields and materials will be a critical task for any device or metrology development from nanoscale to larger scales. Areas of impact over the

Advanced Microscopy for Trace and Bulk Particle Characterization

Ongoing
The goal of this project is to help develop innovative metrologies and measurement protocols for micro/nano-scale analysis of particles. In this project, state-of-the-art optical and electron-based microscopy are used to conduct research for quantitative and qualitative analysis of chemical

Aerodynamic Flow Visualization

Ongoing
Other videos: How Well Do Masks Work? (Schlieren Imaging In Slow Motion!) 3 Ways Of Seeing Invisible Air Flow (Veritasium) The Air You Share | All in This Together Publications "Filter Inserts Impact Cloth Mask Performance against Nano- to Micro-Sized Particles" James G. Radney, Jamie L. Weaver

Amplifiers

Ongoing
We have developed parametric amplifiers based on two different technologies: Josephson Junctions and superconductors with high kinetic inductance, a representation of the kinetic energy of superconducting Cooper-pair charge carriers. Junction-based parametric amplifiers (JPAs) are well suited for

Annual Machine Learning for Materials Research Bootcamp

Ongoing
Four days of lectures and hands-on exercises covering a range of data analysis topics from introduction to python and data pre-processing to advanced machine learning analysis techniques. Example topics include: Identifying important features in complex/high dimensional data Visualizing high

Assessing Pyrrhotite in Concrete

Ongoing
Objective Develop a standard test method and a set of calibration reference materials to quantify pyrrhotite in concrete; document pyrrhotite/aggregate/concrete reactions and rates so that the most deleterious reactions can be efficiently reduced or eliminated; and evaluate proposed mitigation

Atomistic Potentials and the Future of Nanomaterials Metrology

Ongoing
Atomistic simulations are increasingly being used as a tool to understand and predict properties of materials in systems, such as nanomaterials, where direct measurement is time-consuming or extremely difficult. The success of atomistic simulations depends critically on the fidelity of a specific

Automotive Lightweighting

Ongoing
The US auto industry spends $600M per year fixing and tweaking forming dies that do not make correct parts. The primary reason that the dies are inaccurate is that the computer models of the dies utilize materials models that are inaccurate. Upon surveying our industrial partners, we determined that

Autonomous Scanning Droplet Cell

Ongoing
Corrosion impacts a broad spectrum of application areas including infrastructure, transportation, and the military. The annual price tag for corrosion mitigation and remediation is 3.4 % of the US GDP. The team is particularly interested in discovering new metallic glasses (metals without long range

Autonomous Synthesis of Metal-Organic Frameworks

Ongoing
Metal-organic frameworks (MOFs) show great promise for a variety of applications, from industrial gas separation, to catalysis, to PFAS absorption. One challenge to the adoption of these technologies is determining and optimizing the synthesis of these materials. There are large computational

EV Battery Passport

Completed
End-of-life issues associated with EV batteries (EVBs) are estimated to have a steep rise in the coming decades. Given the finite nature of material resources worldwide, developing a circular EV batteries (EVB) infrastructure is needed to keep high value battery materials in the economy, therefore

Biofabrication of Tissue Engineered Constructs

Ongoing
OCT imaging was assessed using a model scaffold-cell system consisting of a polysaccharide-based hydrogel seeded with human Jurkat cells. Four test systems were used: hydrogel seeded with live cells, hydrogel seeded with heat-shocked or fixed dead cells and hydrogel without any cells. Time series

Bioimaging

Completed
Imaging and image analysis are used ubiquitously in biological and biomedical research. One of the great advantages of imaging is its intuitive information content; much can be learned from just a glance at the data. On the other hand, these data generally contain a very large amount of untapped

Biomaterials for Oral Health

Completed
NIST along with its partners has a long commitment to scientific excellence with demonstrated impact in improving the oral health of the public. NIST researchers are leaders in this field and create a community by engaging other researchers, industry, and regulatory agencies to address urgent needs