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Projects/Programs

Displaying 1 - 25 of 144

AAPS Interlaboratory Study: Protein Aggregation and Immunogenicity

Ongoing
To ensure the safety and efficacy of protein-based biotherapeutics, manufacturers strive to avoid unwanted immune responses caused by the biotherapeutic. Protein immunogenicity is a complex topic and depends on multiple factors related to the product, patient profile, and treatment. 1 , 2

Accelerated Weathering Laboratory: Metrology and Technology Transfer

Ongoing
Objective - To maintain, improve and expand capabilities at the NIST Accelerated Weathering Laboratory (AWL) to conduct safe, accurate and traceable aging experiments, develop materials degradation databases, and to transfer the SPHERE technology to industrial stakeholders. What is the new technical

Additive Manufacturing Fatigue and Fracture

Ongoing
Metal additive manufacturing (AM) is not used in fatigue and fracture critical applications despite industrial need. The goal of this project is to enable confident use of metal AM in critical applications through: Advancing metrological practice for AM-specific performance metrics encompassing the

Advanced Composites Pilot for the Materials Genome Initiative

Completed
Many computational programs exist that are being used by industry for predicting properties of polymer composites but their general predictive power is limited by how faithfully the microstructure is represented and how realistically the interfaces are handled. The computations are limited by the

Advanced Materials Metrology

Ongoing
Electromagnetic devices cannot operate without the interaction of electromagnetic waves with materials, and the characterization of the interface between fields and materials will be a critical task for any device or metrology development from nanoscale to larger scales. Areas of impact over the

Advanced Microscopy for Trace and Bulk Particle Characterization

Ongoing
The goal of this project is to help develop innovative metrologies and measurement protocols for micro/nano-scale analysis of particles. In this project, state-of-the-art optical and electron-based microscopy are used to conduct research for quantitative and qualitative analysis of chemical

Aerodynamic Flow Visualization

Ongoing
Other videos: How Well Do Masks Work? (Schlieren Imaging In Slow Motion!) 3 Ways Of Seeing Invisible Air Flow (Veritasium) The Air You Share | All in This Together Publications "Filter Inserts Impact Cloth Mask Performance against Nano- to Micro-Sized Particles" James G. Radney, Jamie L. Weaver

Amplifiers

Ongoing
We have developed parametric amplifiers based on two different technologies: Josephson Junctions and superconductors with high kinetic inductance, a representation of the kinetic energy of superconducting Cooper-pair charge carriers. Junction-based parametric amplifiers (JPAs) are well suited for

Analysis of Copper Incorporation Into Zinc Oxide Nanowires

The lasing capabilities and piezoelectric properties of single ZnO nanowires offer promise for future technologies. However, the photoluminescence of ZnO nanowires differs depending upon the synthesis method and the defects present in the sample. This project was undertaken to characterize zinc

Atomistic Potentials and the Future of Nanomaterials Metrology

Ongoing
Atomistic simulations are increasingly being used as a tool to understand and predict properties of materials in systems, such as nanomaterials, where direct measurement is time-consuming or extremely difficult. The success of atomistic simulations depends critically on the fidelity of a specific

Automotive Lightweighting

Ongoing
The US auto industry spends $600M per year fixing and tweaking forming dies that do not make correct parts. The primary reason that the dies are inaccurate is that the computer models of the dies utilize materials models that are inaccurate. Upon surveying our industrial partners, we determined that

Autonomous Scanning Droplet Cell

Ongoing
Corrosion impacts a broad spectrum of application areas including infrastructure, transportation, and the military. The annual price tag for corrosion mitigation and remediation is 3.4 % of the US GDP. The team is particularly interested in discovering new metallic glasses (metals without long range

Biofabrication of Tissue Engineered Constructs

Ongoing
OCT imaging was assessed using a model scaffold-cell system consisting of a polysaccharide-based hydrogel seeded with human Jurkat cells. Four test systems were used: hydrogel seeded with live cells, hydrogel seeded with heat-shocked or fixed dead cells and hydrogel without any cells. Time series

Bioimaging

Completed
Imaging and image analysis are used ubiquitously in biological and biomedical research. One of the great advantages of imaging is its intuitive information content; much can be learned from just a glance at the data. On the other hand, these data generally contain a very large amount of untapped

Biomaterials for Oral Health

Completed
NIST along with its partners has a long commitment to scientific excellence with demonstrated impact in improving the oral health of the public. NIST researchers are leaders in this field and create a community by engaging other researchers, industry, and regulatory agencies to address urgent needs

Carbon Removal, Capture, Use, and Sequestration

Ongoing
NIST develops benchmark materials, measurements, data, and models to accelerate innovation in and validate performance of materials and technologies for the capture of carbon from air and sequestration in building materials.

Characterization of 3D Photovoltaics

Completed
First Generation (thick layers of crystalline silicon) and Second Generation (thin films of CdTe, CIGS, and related materials) PV devices are both well established in the marketplace, with well defined techniques for fabrication and characterization. Third Generation PV encompasses a wide diversity

Charpy Machine Verification Program

Ongoing
Impact testing is required for many critical applications in the construction, machinery and equipment, defense, and energy markets. Charpy testing provides data needed to ensure the quality and reliability of structural steel products. Over 1,000 machines per year are evaluated for conformance with

Combinatorial Approaches to Thin Film Nanomaterials

Completed
The behavior and performance of nanostructured materials and devices are governed by the chemistry and structure of their surfaces and interfaces. However, chemistry-structure-performance relationships in these systems are complex, so hundreds of experiments can be necessary to determine optimal

Complete Automation and Distribution of Parallel Simulation Tasks

Ongoing
In computational materials science, many problems require the execution of numerous parallel simulation tasks on High Performance Computing (HPC) resources. Often a single published data point is the result of several parallel tasks executed in a specific sequence. Despite the continual improvement