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Projects/Programs

Topic Area
Displaying 601 - 625 of 1638

Gene Delivery Systems

Ongoing
Viral Vectors Viral vectors are a critical tool for delivering DNA or RNA into patient’s cells. Common viral vectors for gene therapy include adenovirus, lentivirus, and adeno associated virus. Administration of viral vectors can occur in vivo or ex vivo , such as for adeno associated virus or
GIAB Logo

Genome in a Bottle

Ongoing
Consortium goals: The Genome in a Bottle Consortium is a public-private-academic consortium hosted by NIST to develop the technical infrastructure (reference standards, reference methods, and reference data) to enable translation of whole human genome sequencing to clinical practice and innovations

Genome in a Bottle Workshops

Ongoing
GIAB has held 1-2 workshops each year since being formed in 2012. These workshops include progress updates, presentations about related work, and planning for new samples and analyses. Following are links to agendas, reports, and presentations from past workshops. Workshop Reports APRIL 2020
Diagram showing the electro-thermo-mechanical relations in a crystal

Genomics of Electronic Materials

Ongoing
We approach this multidimensional characterization problem by developing measurement-based techniques to rapidly quantify all of the relevant properties of thin-film materials, interfaces, and microelectronic structures. We make extensive use of finite-element simulations, as well as linear and non
Photo of broken laminated windshield glass

Glass Evidence Analysis

Ongoing
Quantitative XRF Glass Database Recent research efforts in the forensic trace field have focused on the development of databases to assign a significance to forensic evidence (i.e., to report the strength of an association or exclusion). In the forensic analysis of glass using µ-XRF, samples are
13 tubes each containing an individual glycan in SRM 3655

Glycan Standard Reference Materials

Ongoing
Now Available A glycan-based NIST Standard Reference Material ( SRM 3655 Glycans in Solution) supports the biomanufacturing and protein therapeutics communities with a set of 13 individually-bottled, pure glycoforms including those most commonly observed as N-linked glycans on therapeutic monoclonal

Grasping, Manipulation, and Contact Safety Performance of Robotic Systems

Ongoing
Objective To provide performance metrics, test methods, and associated measurement tools to support next-generation robotic systems having human-like dexterity and force control characteristics. Technical Idea The force sensing and compliance capabilities used in collaborative robots to prevent
Round circles like red and green grapes on the left have one with the globe. Grapes has the A squared.

GReenhouse Gas And Air Pollutants Emissions System (GRA2PES)

Ongoing
The GReenhouse gas And Air Pollutants Emissions System (GRA2PES) uses publicly accessible GHG emissions activity data across multiple economic sectors, including energy production, manufacturing, transportation, agriculture, and land use, among others. The initiative involves the development of
Partial timeline showing the evolution of open-path dual-comb spectroscopy at NIST

Greenhouse Gas and Atmospheric Trace Gas Measurements

Ongoing
Dealing with climate change will require continued reductions in emissions, which in turn will require higher accuracies and precisions for monitoring, reporting and verification. Better monitoring will accelerate local emission reductions as well as being critical to verifying international
Scrubber cropped

Greenhouse Gas Emissions and Transport

Completed
This project develops a high-accuracy reference system for near-industrial-scale CO2 measurements, providing a framework for low-uncertainty emissions data and improving atmospheric dispersion models to reduce uncertainties in greenhouse gas source predictions.
GutMicrobiome

Gut Microbiome Metabolomics Interlaboratory Program

Ongoing
On behalf of the Biosystems and Biomaterials and Chemical Sciences Divisions at the National Institute of Standards and Technology (NIST), we would like to thank you for your interest in our new Gut Microbiome Metabolomics Program. As part of the larger NIST Microbiome Program, this metabolomics
Picture for Hardness and Coating Thickness Standardization and Measurements Project Including Equipment and Standards Organizations

Hardness Standardization and Measurements

Ongoing
DESCRIPTION Purpose: Provide measurement traceability for the Knoop, Rockwell, and Vickers hardness scales and for coating thickness measurements that are based on magnetic methods. Goals: Harmonization of hardness and coating thickness testing protocols, in pursuit of reduction of measurement
Microscope image of a crossbar array

Hardware Accelerators for Neural Networks

Ongoing
One promising candidate for building a hardware accelerator comes from the field of spintronics, where information is carried by electronic spin rather than charge. Magnetic tunnel junctions are particularly suited because of their multifunctionality and compatibility with standard integrated
Temporal Chip

Hardware Accelerators for Statistical Computing

Ongoing
Finding good solutions to many hard problems, like combinatorial optimization and traveling salesman problems, counterintuitively requires making the estimated solution worse before making it better. This situation results from many hard problems having many “solutions” that cannot be improved

HDX-MS for Biopharmaceutical Analysis

Ongoing
Intended Impact This project is designed to improve, test, and validate hydrogen/deuterium exchange mass spectrometry (HDX-MS) metrology for the determination of dynamical properties of therapeutic proteins and glycoproteins. Objectives Explore structure-function relationships between glycan
Circle with the logo of Health Assessment Measurements Quality Assurance Program initials

Health Assessment Measurements Quality Assurance Program (HAMQAP)

Completed
Participants in the HAMQAP measured concentrations of nutritional and toxic elements, fat- and water-soluble vitamins, fatty acids, active and/or marker compounds, and contaminants in samples distributed by NIST.   Samples that represent human intake (e.g., foods, dietary supplements, tobacco) were

Health Information Technology Usability

Completed
The Health Information Technology for Economic and Clinical Health (HITECH) Act provides financial incentives and other support to drive the adoption and meaningful use of EHRs. A recent report funded by the Agency for Healthcare Research and Quality (AHRQ), however, identified key shortcomings

Health IT at NIST - Program Overview

Ongoing
As health IT has become a top priority around the nation, it is clear that standards and interoperability are key to the fulfillment of the goals of health IT: Higher quality and more efficient care. Seamless, secure, and private movement of data between healthcare providers and consumers without

Hierarchical Materials

Ongoing
The STG develops the methods and metrology that will lead to the understanding of the structure-property relationships of hierarchical composites in real medical PPE or protective applications, which heretofore has been lacking. This work establishes in situ monitoring of advanced manufacturing
High Amplification Laser-pressure Optic

High Amplification Laser-pressure Optic (HALO)

Ongoing
We have assembled a high-accuracy laser power meter based on radiation pressure with multiple reflections of the laser on the sensing mirror. A custom electrostatic force balance supports a high-reflectivity sensing mirror upon which a high-power continuous wave laser beam is incident at ~ 45
High Assurance Domains Infor Graphic

High Assurance Domains

Ongoing
NIST's Trustworthy Networks Program seeks to reduce systemic technical vulnerabilities in the foundation of the Internet and other critical network infrastructures. The objectives of NIST’s High Assurance Domains (HAD) project are to design, standardize and foster wide scale adoption of technologies
A double-helix rheometer measuring the viscosity of mortar.

High Performance Computing

Ongoing
Current HPC technology broadly consists of: Leadership systems, such as the Department of Energy INCITE systems. Production Systems, such as clusters We work on both types of systems. For example, our work on the Rheology or Flow Properties of Concrete (see pages 15-16 in the latest INCITE report)