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A NIST–FDA–NIAID Co-Organized Workshop
This workshop aims to advance AI/ML applications in flow cytometry and related data. The workshop will focus on overcoming challenges and identifying solutions including essential measurements, reference controls, AI-ready reference data and ML/AI models. These efforts will target emerging applications in disease diagnosis, therapeutic development, manufacturing, and clinical trials as well as dosing and monitoring.
| Day | Time | Session |
|---|---|---|
Monday, | 9:00 am – 9:05 am | Welcome |
| 9:05 am – 9:40 am | Setting the stage Max Qian, PhD, J. Craig Venter Institute, Featured Presentation, |
| 9:40 am – 10:10 am | Federal Agency Introductions • National Institute of Standards and Technology (NIST) • US Food and Drug Administration (FDA) • National Institute of Allergy and Infectious Disease, US National Insititutes of Health (NIAID/NIH) |
| 10:10 am – 10:30 am | Regulatory perspectives on the use of artificial intelligence Hussein Ezzeldin, FDA |
| 10:30 am – 11:00 am | Coffee break |
| 11:00 am – 12:30 pm | Flow cytometry in research and the clinic – Part I • Thomas Liechti, Roche and ISAC, Featured Presentation, Immunology with high-dimensional flow cytometry • Josef Spidlen, BD Life Sciences, Data Driven Insights and Future Trends • Guang Fan, Oregon Health & Science University, Title TBA • Yu-Fen (Andrea) Wang, AHEAD Medicine, Title TBA |
| 12:30 pm – 1:30 pm | Lunch |
Monday,
| 1:30 pm – 2:30 pm | Flow cytometry in research and the clinic – Part II • Kamila Czechowska-Kusio, Metafora Biosystems, Title TBA • Speaker TBA, National Cancer Institute, Title, TBA • Panel Discussion |
| 2:30 pm – 3:00 pm | Challenges and potential solutions for AI/ML applications – Part I • Holden Maecker, Stanford University, Featured Presentation, Methods for producing high-quality clinical flow data |
| 3:00 pm – 3:30 pm | Coffee break |
| 3:30 pm – 4:30 pm | Challenges and potential solutions for AI/ML applications – Part II • Ryan Brinkman, Dotmatics, Inc., Title TBA • Xing Qiu, University of Rochester, Integrating flow cytometry and bulk transcriptomics for cell type-specific gene expression analysis • Panel Discussion |
| 4:30 pm – 5:10 pm | Updates from flow data repositories • ImmPort by NIAID/NIH, Speaker TBA • FlowRepository by ISAC, Jonathan Irish |
Thursday,
| 9:00 am – 10:30 am | Updates on centralized data analysis of interlaboratory study I • Interlaboratory study overview, Lili Wang and Paul DeRose, NIST • Review of data from consortium interlaboratory studies and LabCAS data repository, John Elliott, NIST • Working Group 3 (WG3) centralized data analysis, Santosh Putta, BioLegend - Revvity |
| 10:30 am – 11:00 am | Coffee break |
| 11:00 am – 11:30 am | AI/ML Infrastructure National resources overview, Varun Chandola, National Science Foundation |
| 11:30 am – 12:30 pm | Panel discussion and workshop conclusion Exploring potential solutions for AI/ML in flow cytometry applications. |
| 12:30 pm – 1:30 pm | Lunch |
Thursday, | 1:30 pm – 5:00 pm | NIST Flow Cytometry Standards Consortium closed session |