The NIST Intelligent Systems Division (ISD) has, for over 30 years, performed research in many aspects of intelligent and complex systems for manufacturing. Prior and ongoing ISD work includes research in robotics, machine tools, coordinate measuring machines, mining equipment, autonomous underwater and land vehicles, and the underlying architectures, sensors and perception subsystems, interface standards, tools, simulation, and performance metrics used in their development and evaluation. We have learned from our early work in such efforts as the NIST Automated Manufacturing Research Facility (AMRF), that many of the technical issues associated with intelligent systems in the manufacturing domain, are universal for intelligent systems in general. This unique experience base has made ISD a valuable, and sought-after partner for a number of other agency funded efforts. For example, ISD has led and/or participated in projects to evaluate the performance of systems such as lane departure warning systems, collision avoidance systems, autonomous military vehicles, bomb-disposal robots, text-translation systems, soldier-worn sensor systems, and robots for urban search and rescue. In addition, ISD has been able to leverage other agency funds to advance our research in core elements of intelligent systems, including control, perception, planning and knowledge systems which we apply to intelligent and complex manufacturing systems and their performance measures.