Cygan, Z.
, Cabral, J.
, Beers, K.
and Amis, E.
(2005),
Microfluidic Platform for the Generation of Organic-Phase Microreactors, Langmuir
(Accessed January 2, 2025)
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Microfluidic Platform for the Generation of Organic-Phase Microreactors
Published
Author(s)
, J Cabral, ,
Abstract
Rapid prototyping photolithography of a thiolene based resin was used to fabricate microfluidic devices stable to aliphatic and aromatic organic solvents. The swelling of the thiolene resin in various organic solvents was quantified and the solvent resistance properties of these microfluidic devices are described. Discrete droplets of hexanes and toluene of uniform size were generated in a water matrix containing SDS surfactant (SDS = sodium dodecylsulfate). Variation of water and organic flow rate in the fluidic channels was used to control droplet size and separation, and droplet composition could be controlled by varying flow rates of two joined organic streams. Organic phase synthetic reactions within the droplets were demonstrated with the bromination of alkenes inside of droplets of benzene.Citation
Langmuir
Volume
21
Issue
No. 8
Pub Type
Journals
Keywords
droplet formation, microfluidics, microreactors, photolithography, solvent swelling
Citation
Issues
If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.
Created April 1, 2005, Updated February 19, 2017